In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance.
We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins.
Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance.
Access the full show notes for this episode at hubermanlab.com.
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Timestamps
00:00:00 Dr. Craig Koniver
00:04:52 Sponsors: Joovv & BetterHelp
00:07:40 What is a Peptide?
00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health
00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation
00:18:43 BPC-157, Inflammation
00:23:27 BPC-157, Injection & Oral Forms; Injury Repair
00:28:43 Sourcing, Anabolic Steroids, Testosterone
00:34:48 Black & Gray Market, Compounding Pharmacies, Purity
00:38:20 Sponsor: AG1
00:39:51 Partnering with a Physician, LPS
00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses
00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone
00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides
00:58:45 Sponsor: Function & Eight Sleep
01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health
01:05:16 Prescriptions, Physicians & Trust
01:14:09 Agency in Your Health
01:17:13 MK-677, Appetite
01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing
01:21:10 Methylated B Vitamins, Homocysteine
01:24:47 Peptides for Sleep, Pinealon, Epitalon
01:31:03 Glycine, Liver Detoxification; Dosage
01:37:19 GLP-1, Compounding Pharmacies
01:39:03 Stem Cell Therapy, PRP
01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health
01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses
01:50:20 Covid, NAD Infusion, NMN & NR Supplements
01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR
02:07:53 PT-141, Vyleesi, Libido; Nausea
02:10:57 FDA Approval & Removal, Pharmaceutical Companies
02:20:17 Positivity, Mindset & Health
02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter
Disclaimer & Disclosures