Martha Johnson & Mark Gane in conversation with David Eastaugh

After another long layoff from being an active performing entity, Martha and the Muffins released a video and downloadable song in May 2020 called "Stay Home and Dance". A reworking of the 1984 M+M track "Come Out and Dance", the new song and video was released in response to the stay-at-home orders surrounding the COVID-19 pandemic.

In 2021 they released the compilation Marthology: In and Outtakes, collecting rarities and demo versions of past songs. At the same time they indicated that they were working on a new album, tentatively slated for release in 2022.