Ep. 588 - For the first time in their careers, Kyler Murray and Patrick Mahomes will go head-to-head. It is one of the more intriguing matchups in Week 1. Craig Grialou and Paul Calvisi break down Sunday's game at State Farm Stadium. Now while the two quarterbacks and their respective offenses have received much of the attention this week, the guys make sure not to neglect the defenses. In fact, defense may be the determining factor. Both teams have major question marks on that side of the ball.

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