In this episode of the IJGC podcast, Editor-in-Chief, Dr. Pedro Ramirez, is joined by Drs. Vandré Carneiro and Glauco Baiocchi to discuss the LESSER trial. Dr. Carneiro is the head of the Department of Gynecologic Oncology at the Instituto de Medicina Integral Professor Fernando Figueira (IMIP). He is also Director of the Department of the Hereditary Cancer Program of Hospital de Cancer de Pernambuco. Dr. Baiocchi is the head of the Department of Gynecologic Oncology at the AC Camargo Cancer Center. He is also the president of the Brazilian Gynecologic Oncology Group – EVA Group.

Highlights:

- Hysterectomy is safe and potentially non-inferior to modified radical hysterectomy in early-stage cervical cancer.

- The LESSER supports simple hysterectomy as a substitute for radical hysterectomy in patients with cervical cancer ≤2 cm.

- The SHAPE trial will provide more concrete data on the role of simple hysterectomy for early-stage cervical cancer.