Six nationally-ranked matchups and several others in the spotlight pitting unbeatens against one another — college football’s Week 4 schedule is what we’ve waited for throughout the offseason, the first separation weekend among many of the nation’s elite and perceived contenders. Ohio State-Notre Dame is a headliner, along with Colorado-Oregon and Ole Miss-Alabama.
Not only are this week’s predictions packed with matchups pitting top 25 teams, but FSU-Clemson is arguably the most important game in September within the ACC and the winner of Memphis-Missouri in St. Louis should produce a new team in next week’s AP Poll.
Here are our predictions for Week 4’s top games and our explanation on where your money should go in each matchup:
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