He was born of pious and noble parents in Rome in the time of the Emperor Honorius. His parents, Euphemianus and Agalais, set a high standard of godly living: his father, though wealthy, sat down to dine only once a day, at sunset. By his parents' arrangement Alexis was married at a young age. However, without ever living with his new wife, he fled to Edessa in Mesopotamia, where he lived in asceticism for eighteen years, presenting himself as a beggar in order to avoid the praise of men. When, despite his efforts, he began to be known as a holy man, he fled the city and took ship for Laodicea. By divine providence, the ship was blown off course and forced to land in Rome. Taking this as a sign, Alexis, still disguised as a beggar, returned to his parents' house, where he sat at the gates, unrecognized by any of his family. His father, not knowing who he was, allowed him to live in a hut in his courtyard. There Alexis spent another seventeen years, living only on bread and water. He died clutching a piece of paper on which he had revealed his true identity. At the time of his death, the pope of Rome heard a voice saying "Look for the Man of God," and revealing where he should look. It is said that the Emperor Honorius, the Pope and a large retinue came to the house, where they found Alexis dead in his tiny hut, his face shining like the sun. His parents and wife were at first overcome with grief to learn that their son and husband had been secretly living near them, but they were comforted when they saw that his body healed the sick and exuded a fragrant myrrh. Thus they knew that God had glorified him. His head is preserved at the Church of St Laurus on the Peloponnese.