Psychopharmacology and Psychiatry Updates
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295 episodes
In this episode, we discuss the groundbreaking FDA approval of zuranolone, the first oral medication specifically targeting postpartum depression. COULD ZURANOLONE'S NOVEL MECHANISM OF ACTION AS AN ALLOPREGNANOLONE AGONIST HERALD A NEW ERA OF RAPID-ONSET, TARGETED TREATMENTS FOR THIS DEBILITATING CONDITION AFFECTING 1 IN 8 NEW MOTHERS? Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we explore practical clinical tips for using broad-spectrum micronutrient supplements to treat mental health conditions. CAN AN INDIVIDUAL'S NUTRITIONAL NEEDS SURPASS POPULATION STANDARDS? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we examine whether first-trimester exposure to the antipsychotic olanzapine increases the risk of major fetal malformations. DOES STOPPING MEDICATION ABRUPTLY ALSO CARRY RISKS? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we delve into the safety considerations of using broad-spectrum micronutrient formulas in mental disorder treatment, mainly how these supplements can interact with other medications. IS IT SAFE TO USE THESE FORMULAS ALONGSIDE ANESTHESIA DURING SURGERY? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we explore the potential of NSAIDs in delirium prevention. However, NSAIDs come with risks, such as GI bleeding or kidney injury. CAN NSAIDS REALLY HELP PREVENT DELIRIUM, AND IF SO, HOW? Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we explore the unconventional yet promising treatment modality of using broad-spectrum micronutrient formulas in mental health care. We discuss the research and clinical trials that have been undertaken to test combinations of vitamins and minerals, focusing on their safety and efficacy. WHAT ARE THE POTENTIAL SIDE EFFECTS OF USING BROAD-SPECTRUM MICRONUTRIENT FORMULAS? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we discuss an insightful study by Strawn et al. that utilized a mega-analysis approach, combining data on over 900 MDD patients across lifespan treatment trials to elucidate differences in antidepressant treatment outcomes based on patient age. Does antidepressant efficacy differ across developmental stages—children, adolescents, and adults? Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
WHAT ARE SOME COMMON SIGNS THAT SUGGEST A CANCER PATIENT MAY BE DEVELOPING DELIRIUM? In this episode, we explore the complex issue of delirium in advanced cancer patients. We discuss important considerations regarding medication management, the importance of distinguishing terminal from reversible delirium, and the role of antipsychotics and benzodiazepines in treatment. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we discuss the treatment of agranulocytosis or neutropenia in patients on clozapine therapy, a rare yet serious scenario that clinicians may encounter. We delve into the possibility of rechallenging clozapine treatment after such an event and explore the use of colony-stimulating factors. What's the likelihood of agranulocytosis while prescribing clozapine long term? Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we delve into the management of anxiety in cancer patients, including the effective psychotherapeutic interventions and pharmacologic options for treating anxiety in this vulnerable group. The episode also touches on the importance of cultural sensitivity and patient education when managing anxiety in cancer patients. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. __ __
In this podcast episode, Dr. David Rosenberg explores practical strategies to asess and manage common antidepressant side effects in the pediatric population. Get useful takeaways regarding activation, insomnia, withdrawal symptoms, and more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this podcast episode, Jaroslava Salman, M.D., discusses the treatment options for depressed patients with cancer. Stay a step ahead in your practice with practical tips on which psychotherapies are helpful, which antidepressants to use and for how long, what to be mindful of, and even insights into prescribing stimulants. Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D. __ __
In this podcast episode, Dr. Vivien Burt delves into a study on brexanolone for women with postpartum depression, anxiety, and insomnia. Listen in and find out the effect and time frame of brexanolone on these symptoms. Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. David Rosenberg offers practical insights into treatment optimization for youth with tic disorders. Listen in and find out which treatment modality takes precedence, which factors need to be considered, how long to use medication, and more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. David Rosenberg expertly addresses the questions on what to do when your adolescent patient has ADHD but uses cannabis. Should you prescribe stiimulants or not? And what if they just want stimulants for better test scores? What do you do? Listen in as Dr. Rosenberg offers useful takeaways to help you with these (all too common) dilemmas. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. David Rosenberg delves into tic disorders and psychiatric comorbidities in youth. This includes ADHD, OCD, anxiety and depression, and disruptive behaviors. Jump in and listen to practical treatment options for these cases, and stay one step ahead in your clinical practice. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
CANMAT presents a spectrum approach to mixed states. In this podcast, Dr. Jim Phelps delves into this and the DSM-5 approach, where mixed states became a specifier that can be added to a diagnosis of unipolar depression, effectively creating a spectrum approach to the diagnosis of mixed mood disorders. So, what’s a clinician to do treatment-wise? Should we or should we not use antidepressants when 4 specific symptoms are present? Find the answer to these and other questions in this podcast. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. __ __
In this podcast episode, Dr. David Rosenberg provides a much-needed understanding of tic disorders in children and adolescents. Listen in to learn what a typical course of this disorder could look like, why you may not need to substitute methylphenidate in these patients, what happens when patients supress tics, and much more. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. David Rosenberg explores a review on metformin for youth on SGAs. Is it effective in mitigating weight gain in this population? And more importantly, should you prescribe it ASAP? Listen in as Dr. Rosenberg answers these questions and others. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. Jim Phelps discusses the issue of diagnosing bipolar disorder within the framework of a mood spectrum. How bipolar should a patient be before switching treatment strategies? Listen in for tips and practical takeaways to answer this question and guide decision making. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. __ __
In this podcast, Dr. Schenck discusses zolpidem-induced sleeping disorder and eating disorder. Listen and find out important tips and considerations, such as this being more common in females, alerting bed partners, being careful with zolpidem doses over 10 mg, and more. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. __ __
Cariprazine may be a good option for pediatric patients with schizophrenia and bipolar I disorder. Listen as Dr. Rosenberg summarizes study findings, which may broaden your options with children and adolescents. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
This podcast explores medication associated with sleepwalking and sleep driving, as well as recommendations for clinicians when prescribing them to patients. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we explore whether the olanzapine–samidorphan combination helps with psychosis while halting weight gain. We also look into the cost vs benefit of the combination as well as the metabolic side effects. Faculty: James Phelps, M.D. Host: Richard Seeber, M.D. __ __
Can melatonin reduce the risk of suicidality, bodily injuries, falls, and accidents in children and adolescents? In this episode, we explore a study that delves into this question. Discover how sleep disturbances impact young individuals' health, development, cognitive skills, emotional regulation, and behavior. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
Do you know what sleep-related eating disorder (SRED) is and how it intertwines sleep and eating pathologically? In this episode, we delve into an in-depth analysis of SRED, elucidating its diagnostic criteria, key characteristics of the diagnosis, and some intriguing aspects related to this disorder. Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D. __ __
This episode explores the controversial role of pimavanserin in treating psychosis in Parkinson's disease. How does it compare with quetiapine or clozapine? Sneak peek: All of these medications are effective, yet none distinctly surpasses the others. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. __ __
Pediatric bipolar disorder treatment has evolved significantly since 2005, moving beyond lithium to several FDA-approved treatments. However, the challenges remain: How do we choose the first-line treatment? How can we mitigate and monitor side effects? In this episode, we discuss the latest practice treatment algorithms for pediatric bipolar disorder. Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D. __ __
Can pharmacogenomic testing improve the selection and dosing of antidepressants in patients with MDD? In this episode, we explore the findings of the PRIME Care trial and discuss the clinical significance of these tests. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D. __ __
In this episode, we discuss the role of broad-spectrum micronutrients (BSMs) in managing symptoms of ADHD. We examine the rationale behind opting for alternative therapies for this condition and dissect the outcomes of an RCT involving BSMs for ADHD. Could micronutrients provide a comprehensive strategy for treating ADHD, thereby enhancing overall mental wellness? Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D. __ __
