Science History Podcast
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Peter Agre received the 2003 Nobel Prize in Chemistry for his discovery of aquaporins. Peter is a Bloomberg Distinguished Professor in Molecular Microbiology and Immunology at Johns Hopkins Bloomberg School of Public Health, and he also directed the Johns Hopkins Malaria Research Institute until 2023. Today we discuss the history of malaria research, and Peter reflects on being a scientist. The interview is followed by Peter's keynote lecture for the University of Arizona One Health symposium, which he gave on February 12, 2024.
In 1994, while attending graduate school at the University of California, Berkeley, I had the pleasure of seeing a lecture by Oliver Sacks in which he discussed his work on sleeping sickness and various other neurological disorders. He also discussed his thoughts on the economy of a life. Today's episode is that lecture in full, with all the insights and charm that was Oliver Sacks.
Novichok is the most deadly chemical weapon ever developed. With us to discuss the history of Novichok is Vil Mirzayanov. Vil worked in the secret Soviet chemical weapons laboratory that developed Novichok. He revealed its existence to the world in 1991 and was then arrested by the Russian counterintelligence service and prosecuted in a secret trial. He won his freedom with the help of an international group of scientists, including three who have appeared as guests on this podcast. He then immigrated to the United States and published his story in the book , published in 2009 by Outskirts Press.
How could a brilliant scientist and mathematician, an innovator in quantum theory, who worked closely with Jewish colleagues, become an ardent Nazi? How did this man, who has a field of mathematics named after him, escape the scrutiny of his colleagues? And what happened to him upon the collapse of Nazi Germany? The scientist who straddled this strange world of physics and Nazism was Pascual Jordan. With us to explain the history of Pascual Jordan is Ryan Dahn. Ryan is a writer, editor, science historian, and translator. He is the books editor at Physics Today, the flagship physics magazine of the American Institute of Physics.
Many of the most important secrets held in international contests are technological or scientific in nature, and wars are often settled due to technological superiority of one side over the other. This leads spy agencies to employ all manner of trickery and tools to obtain those secrets. With us to explore the history of scientific espionage is Eli Lake. Eli was a senior national security correspondent for and , and a syndicated columnist with Bloomberg. Eli is now a columnist for the Free Press and the host of the Re-Education Podcast on Nebulous media. Eli is also a contributing editor for Commentary Magazine.
A retrospective on the Franck-Hertz experiment, which resulted in James Franck and Gustav Hertz receiving the 1925 Nobel Prize in Physics. Image credit: By Infoczo - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=35281920
A retrospective on James Franck, recipient of the 1925 Nobel Prize in Physics.
The ability to extract DNA from ancient fragments of biological material has revolutionized our understanding of recent evolutionary history, including human evolution and phylogeography. Analysis of ancient DNA in tandem with radiocarbon dating, along with traditional archeological techniques, has led to a flurry of discoveries. With us to discuss this research is Maanasa Raghavan. Maanasa is a Neubauer Family Assistant Professor of Human Genetics at the University of Chicago.
The world just experienced a devastating pandemic, yet in the context of historical pandemics, COVID-19 was a relatively minor event in the history of disease. What do we know about the history of pandemics, including before written records, and what can we learn from this history? With us to answer these and other questions about the origins of epidemics and pandemics is Leslie Reperant. Leslie graduated with a doctorate of veterinary medicine at the National Veterinary School of Lyon, France in 2004 and obtained a PhD at Princeton University in the Department of Ecology and Evolutionary Biology in 2010. Leslie's doctoral and post-doctoral studies focused on the interplay between the pathogenesis and evolution of influenza viruses, and on factors driving pathogen emergence and spread. Leslie is the author of , published in 2023 by Johns Hopkins University Press.
Before the advent of the germ theory of disease in the 1870s, quarantine provided one of the few effective means to prevent or alleviate epidemics. The Lazaretto quarantine station in Philadelphia illustrates the history of quarantine both before and after the discovery of pathogenic microbes. With us to explore the history of 18th and 19th century quarantine in Philadelphia, and what it meant for public health, is David Barnes. David teaches the history of medicine and public health at the University of Pennsylvania, where he is an Associate Professor of History and Sociology of Science. David received a BA in history from Yale in 1984 and a Ph.D. in history from the University of California, Berkeley in 1992. His books include (University of California Press, 1995), (Johns Hopkins University Press, 2006), and (Johns Hopkins University Press, 2023).
What are the commonalities between scaling the world's highest peaks and tackling the most challenging pollution problems? What was it like to enter the worlds of climbing and chemistry as a woman in the 1960s and 70s? With us to answer these questions is Arlene Blum. Arlene completed a bachelor's degree at Reed College in 1966 and a PhD in biophysical chemistry at Berkeley in 1971. She was a pioneering alpinist early in her career and a founder of the Green Science Policy Institute later in her career. She is the author of , published by Counterpoint in 1980, and , published by Harcourt in 2005.
Any intellectual endeavor runs the risk of bias. Today we explore ways in which political ideology interferes with scholarship, particularly in the social sciences, with a focus on social psychology. My guest is Lee Jussim, a distinguished professor of social psychology and the leader of the Social Perception Laboratory at Rutgers University. Lee is a prolific author and studies stereotypes, prejudice, and discrimination; political radicalization; and other problems that impede science and society. Lee's books include , which received the American Association of Publishers award for best book in psychology, as well as the edited volumes , , and . Lee is also a founding member of the Heterodox Academy, the Academic Freedom Alliance, and the Society for Open Inquiry in the Behavioral Sciences.
The world's environmental problems demand solutions for the common good, which in turn necessitate environmental diplomacy. With us to untangle the messy history of environmental diplomacy is Mark Lytle. In addition to his long tenure as a professor at Bard College, Mark has taught at Yale, Vassar, and University College Dublin. Mark's books include , , , and .
Certain fields of science attract broad interest because of what they tell us about humanity, and no field does this more directly than paleoanthropology. Today we explore the history of paleoanthropology with a focus on Louis and Mary Leakey, who made key discoveries at an inflection point of our understanding of human evolution. With us to discuss this history is Evan Hadingham. Evanis the Senior Science Editor of the award-winning PBS series . Today we discuss his new book, , published in partnership with the Leakey Foundation in 2021.
How could a conservation easement be anything other than a great thing? With us to answer this question are Jaimi Dowdell and Andrea Januta, both of whom are investigative reporters and data journalists with Reuters. Jaimi and Andrea were part of the Reuters team that won the 2021 Pulitzer Prize in Explanatory Reporting. Today we discuss their Reuters special report entitled "How Boeing created a nature preserve that may also preserve pollution", published on July 20, 2022.
For thousands of years, scholars have struggled with what it means to be human. One critical dimension of humanity is foresight, and with us to decipher the evolution of foresight is Thomas Suddendorf. Thomas is a professor at the University of Queensland, where he investigates mental capacities in young children and in animals to answer fundamental questions about the nature and evolution of the human mind. Thomas is the author of over 140 research articles and two books: , published in 2013 by Basic Books, and (with co-authors Jonathan Redshaw and Adam Bulley), published in 2022, also by Basic Books. Today we discuss archaeological finds related to stone tools, fire, hunting, ornaments, containers, burial, watercraft, maps, music, and storytelling - and what they tell us about the evolution of foresight.
Johan Rockström and colleagues first proposed the concept in 2009 of planetary boundary threats and a safe operating space for humanity. This conceptual framework clarifies environmental problems that are of planetary significance, such as biodiversity loss, climate change, and stratospheric ozone depletion. The most recently articulated planetary boundary threat, or set of threats, relates to chemical pollution of the biosphere. With us to unpack planetary boundary threats as they relate to pollution is Bethanie Carney Almroth. Bethanie is a professor at the University of Gothenburg, where she researches threats posed to our planet due to the immense number and quantities of synthetic chemicals released into the environment.
The Wall Street Crash of 1929 and the ensuing worldwide Great Depression left families in economic shock and despair. International trade collapsed to less than half of its previous levels and unemployment skyrocketed. Into this devastating mess stepped Franklin Delano Roosevelt, who began his long presidency in 1933. FDR spearheaded a series of programs known as the New Deal to revive the United States. The most popular of these was the government work relief program called the Civilian Conservation Corps, which ran from 1933 to 1942. Three million American men joined the Corps, gaining skills and employment while also attending to widespread conservation problems. With us to explain the significance of the Civilian Conservation Corps is Neil Maher. Neil is a professor of history in the Federated History Department at the New Jersey Institute of Technology and Rutgers University, Newark, and he is the author of and .
The ways people think about matters both big and small, from climate change to daily tasks, impact the outcomes. Throughout the history of science and society, key insights arose through a thought process of simplification and subtraction, though the human tendency leans towards complication and addition. Today I discuss the power of subtraction with Leidy Klotz. Leidy is a professor at the University of Virginia, where he studies the science of design. He is the author of , published in 2021 by Flatiron Books.
No matter our claims to the contrary, we are all biased in our perceptions and beliefs. But bias is not random and its directions relate to our evolutionary history and culture, especially to how these interface with human sociality. With us to decipher bias is Jim Zimring. Jim is the author of , published b Cambridge University Press in 2019, and published by Columbia University Press in 2022. Today we discuss flawed thinking about fractions, the No True Scotsman Fallacy, what we see when we read, heuristics, stories vs. statistics, confirmation bias, the prosecutor’s fallacy, cherry picking, tautology, hindsight bias, the Bible code, the fine-tuning argument, armor on WWII bombers and the Anthropic Principle, and the reproducibility crisis.
The oceans have been used as the dumping grounds for all manner of toxic waste. Outrage over such dumping led to the Marine Protection, Research, and Sanctuaries Act of 1972 in the United States and the London Convention on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter in 1975. Today I discuss the dumping of DDT and other wastes off the coast of Southern California with Dave Valentine. Dave completed a BS in chemistry and biochemistry at the University of California San Diego in 1995, followed by an MS in chemistry also at UCSD the following year. He then completed MS and PhD degrees in earth system science at the University of California Irvine in 1998 and 2000. Dave is now the Norris Presidential Chair in Earth Science at UC Santa Barbara. He has participated in 25 oceanographic expeditions, including 13 as chief scientist.
Many landmarks of environmental history share a connection with a single molecule: DDT. During and after the Second World War, it was broadcast into the environment at a scale that far surpassed the applications of any prior chemical. The public met this mass spraying of DDT with enthusiasm, as the war proved it to be highly effective against the vectors of malaria, yellow fever, typhus, and other insect-borne diseases. But these public health successes were short-lived as insects quickly evolved resistance. Nevertheless, DDT use skyrocketed around the world, especially in agriculture. It was also used on a massive scale in forestry, in the Sisyphean fight against invasive insects, and in the home, where clever companies impregnated all manner of commercial products with DDT, ranging from bug bombs to house paint to wallpaper for the nursery. Due primarily to its massive impact on the environment, but also to effects on human health, a backlash ensued, driven most forcefully by Rachel Carson’s 1962 book . The chemical was banned throughout the world in the 1970s and 80s, and yet its story continued. With us to unravel this complex tale, and its relation to science denial and corporate malfeasance, is Elena Conis. Elena is a historian of medicine and an Associate Professor in the Graduate School of Journalism and Department of History at the University of California, Berkeley. Her research focuses on scientific controversies, science denial, and public understanding of science. She is the author of , and a co-editor of . Today we discuss her most recent book,
At the start of the 20th century, physicists probed the structure of nature. Their discoveries changed our fundamental understanding of matter, of life, and of war. At the center of these discoveries stood the Danish physicist Niels Bohr. Bohr approached problems of atomic structure and quantum theory with a philosophical perspective and an ability to skirt paradoxes with his principle of complementarity. Perhaps as important as Bohr’s discoveries on the atom was his hosting of international collaborations at his institute in Copenhagen, which in turn led to fundamental insights in physics and chemistry. Bohr also played significant humanitarian and diplomatic roles during World War II in Denmark, Sweden, the United Kingdom, and the United States. Many Jewish refugee scientists passed through Bohr’s institute after escaping Nazi Germany, and Bohr then facilitated their immigration to safe harbors. With us to decipher Bohr’s complex legacy is John Heilbron. John is a member of the International Academy of the History of Science, for which he served as president from 2001-2005. He is also a member of The Royal Swedish Academy of Sciences, The American Academy of Arts and Sciences, and The American Philosophical Society. He is the recipient of many awards for his scholarship on the history of science.
The advent of agriculture over 10,000 years ago forever altered the trajectory of humanity. Communities grew larger until cities and nations dotted the landscape, labor became specialized, new diseases emerged, civilizations flourished and vanished, warfare increased in scale and lethality, and people colonized every corner of the globe. Agriculture facilitated the exponential growth of the human population, which necessitated ever greater efficiency and productivity and eventually led to the industrialization of farming. But this efficiency has come at a cost – the loss of crop varieties and the local knowledge and cultural practices associated with those crops. With us to understand these radical changes in agricultural practices, and their implications for society, is Helen Anne Curry. Helen is an Associate Professor in the Department of History and Philosophy of Science at the University of Cambridge and a fellow of Churchill College. Her research focuses on the histories of seeds, crop science, and industrial agriculture. She is author of and .
The brain is the most mysterious and complex organ of the body, and when things go awry, we may be confronted with personal tragedy and we may gain insights on what it means to be human. With us to discuss neurological disorders and the history of their discovery is Sara Manning Peskin. Sara completed an AB in biochemistry at Harvard University in 2009, an MS in cellular and molecular biology at the University of Pennsylvania in 2013, and an MD also at U Penn in 2015. She completed postgraduate training and a fellowship in various aspects of neurology also at U Penn, where she is now an Assistant Professor of Clinical Neurology. Today we discuss a cornucopia of neurological disorders, including Huntington’s disease, Alzheimer’s disease, Lewy body dementia, Pick’s disease, pellagra, and kuru disease (and its association with cannibalism) – all drawn from the pages of her new book, , published in 2022 by W.W. Norton & Company.
Nothing is so intertwined with human success and folly as economics. The economy, for better or for worse, drives much of our fate from our household budget to our national policies to the outbreak of war. But economic activity also has profound effects on the environment and a close inspection of economics opens the question of whether humans can live sustainably on the only planet we have. The field of economics that focuses on sustainability and the environmental costs of economic activity is ecological economics. With us to discuss this field is one of its founders, Herman Daly. Herman received a B.A. in economics from Rice University in 1960 and a PhD in from Vanderbilt University in 1967. He was a professor of economics at Louisiana State University until 1988, and then served as senior economist in the environment department of the World Bank until 1994. He then joined the faculty at the University of Maryland in the School of Public Affairs. Herman is the author of over 100 articles in professional journals, as well as many books, including: Toward a Steady-State Economy (1973), Steady-State Economics (1977), Valuing the Earth (1993), Beyond Growth (1996), Ecological Economics and the Ecology of Economics (1999), Ecological Economics: Principles and Applications (2004), and Ecological Economics and Sustainable Development (2007). He is co-author with theologian John B. Cobb, Jr. of the award-winning book, For the Common Good (1989). He also co-founded the journal Ecological Economics and the International Society of Ecological Economics. Herman has received too many awards to list here, but they include Sweden’s Honorary Right Livelihood Award, the Heineken Prize for Environmental Science from the Netherlands, the Sophie Prize for Environment and Development from Norway, the Medal of the Presidency of the Italian Republic, the Lifetime Achievement Award from the National Council for Science and the Environment, and the Blue Planet Prize.
The 60s hosted the space race between the United States and the Soviet Union, which occurred in the midst of the Vietnam War, the Cold War, and civil unrest. How did the culture wars of the 1960s relate to the space race, especially in the United States? How did the Civil Rights Movement, the New Left, environmentalism, the women’s movement, and the Hippie counterculture influence NASA, and vice versa? With us to answer these questions is Neil Maher. Neil received a B.A. in history from Dartmouth College in 1986, an MA in U.S. history from New York University in 1997, and a Ph.D. in history, also from New York University, in 2001. He is a professor of history in the Federated History Department at the New Jersey Institute of Technology and Rutgers University, Newark, where he teaches environmental history, political history, and the history of environmental justice. Neil has received numerous fellowships, awards, and grants from the Smithsonian Institution, NASA, Harvard University’s Charles Warren Center for Studies in American History, and Ludwig Maximilian University’s Rachel Carson Center for Environment and Society in Munich, Germany. His books include (Oxford University Press, 2008), and (Harvard University Press, 2017).
Today’s episode marks the four-year anniversary of the Science History Podcast, where we have explored all manner of science and relevant policy spanning from gravitational waves to bioterrorism. So it is fitting that today’s guest, Dick Garwin, has worked on just about every major scientific and technology problem with a defense application since just after the Second World War, ranging from the first thermonuclear weapon in 1951 all the way to the U.S. response to pandemics. Today we discuss it all, including space nuclear detonations and electromagnetic pulses, spy satellites, anti-submarine warfare, sequential memory for computers, magnetic resonance imaging, laser printers, touch-screen monitors, nuclear weapons testing, nuclear reactor accidents, Ebola, the Iraq War, the BP Deep Water Horizon oil spill, and even gravitational waves. Dick was born in Ohio in 1928. He received a BS in physics from Case Institute of Technology in 1947 at the age of 19, and then a Ph.D. in physics from the University of Chicago in 1949, at the age of 21. Two years later, in 1951, for a summer project at Los Alamos, he designed the first hydrogen bomb. Dick joined the IBM Corporation in 1952, where for over 40 years he helped to design diverse technology with military applications. He also held numerous posts in universities and at the Council on Foreign Relations in New York, in addition to advising presidents on science and technology, from Eisenhower to Kennedy to Johnson to Nixon. He also served on various technical committees for subsequent American administrations, all the way through to the Obama presidency. Dick has published over 500 papers and been granted 47 U.S. patents. He also coauthored many books, including (1977), (1977), (1979), (1980), (1994), and (2001). Dick is a Fellow of the American Physical Society, of the Institute of Electrical and Electronics Engineers, and of the American Academy of Arts and Sciences. He is also a member of the National Academy of Sciences, the National Academy of Engineering, and the National Academy of Medicine. Dick received too many awards to list them all here, but they include the 2003 National Medal of Science, awarded by President George W. Bush, and the 2016 Presidential Medal of Freedom, awarded by President Barack Obama. In sum, he is a treasure of 20th Century American science, and I hope you enjoy this opportunity to hear his thoughts as we tour the last 70 years of science, technology and policy.
Today we explore the history of nuclear disarmament with Zia Mian. Zia is a physicist and co-director of Princeton’s Program on Science and Global Security, part of the School of Public and International Affairs, where he has worked since 1997. His research interests include issues of nuclear arms control, nonproliferation and disarmament, and international peace and security. Zia is co-editor of the journal , and he is the co-author of , published by MIT Press in 2014. He is also co-chair of the International Panel on Fissile Materials. Zia received the 2014 Linus Pauling Legacy Award for “his accomplishments as a scientist and as a peace activist in contributing to the global effort for nuclear disarmament and for a more peaceful world.” He also received the American Physical Society’s 2019 Leo Szilard Award “for promoting global peace and nuclear disarmament”. In 2021, Zia was elected a Fellow of the American Physical Society for “promoting global nuclear risk reduction and disarmament.”
How do we distinguish real science from hogwash? How does real science evolve over time into pseudoscience? Why will science always be plagued with sister movements on the fringe that make us cringe? With us to explore these topics and their relationship to the demarcation problem is Michael Gordin. Michael is the Rosengarten Professor of Modern and Contemporary History and the director of the Society of Fellows in the Liberal Arts at Princeton University. He specializes in the history of modern science in Russia, Europe, and North America, especially issues related to the history of fringe science, the early years of the nuclear arms race, Russian and Soviet science, language and science, and Albert Einstein. He is the author of , which we discuss today, as well as and. Today we discuss diverse topics in fringe science, including Bigfoot, extra sensory perception, UFOs, astrology, alchemy, the ether, Aryan physics, Lysenkoism, phrenology, cryptozoology, Velikovsky, Mesmerism, Uri Geller, cold fusion, and where all of this leaves us as we navigate the waters between science and pseudoscience.
