The Human Upgrade with Dave Asprey

Dave Asprey


For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.

You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.

Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.

Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

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1145 episodes

Unlocking Optimal Health Through Your Genetic Code: Healing from Veganism, Chronic Pain & Stressors - Chris Masterjohn : 1090

Today, we welcome back a guest from the early days of this podcast, fellow former vegan and esteemed researcher and scientist, Chris Masterjohn. Chris Masterjohn earned his PhD in Nutritional Sciences from the University of Connecticut, and has worked as a postdoctoral research associate and Assistant Professor of Health and Nutrition Sciences.  In 2016, he transitioned to entrepreneurship. These days, Chris conducts independent research, consults, develops information products, and creates free content to help people improve their health.  Chris is dedicated to sharing practical principles from complex science, and to the pursuit of truth and continuous learning. He's a biohacker from before the word “biohacking” came to be, appearing on episode 16 of this podcast when I was just getting that movement started, because he not only pays attention to how stuff works in the world and academic research, but he hacks his own body. I've always liked the way he thinks mechanistically about biology, nutrients, and what to eat.  In this conversation, we talk about how to recover from veganism and reverse the effects of oxalates, highlighting the long term health impacts of the vegan diet. His own self experimentation lately is of particular interest to me as he’s been exploring the intersection of genetics and mitochondrial health to heal niche health conditions and even quell extreme fears or stressors. We also talk about the link between energy metabolism and psychological trauma, chronic pain and oxalate overload, and even explore the potential dangers of methylene blue from his latest 58 page research paper breaking down the importance of correct dosing.  If you’re a true biohacker, you’re going to love this deep dive into how minerals and metabolism play a huge role in our biology. (03:47) Genetic Optimization: A New Approach to Healing Chronic Pain & Disease • How his perspective on nutrition has changed since our first episode • The extreme effects veganism had on his health • Using genetics research to find solutions to rare health issues • The role of AI in diagnosing health conditions—now and in the future • Focusing on mitochondria as the root cause to heal health issues  • Access his program: • What will reverse the anti fertility trend? • The psychological rewiring required to heal chronic disease states  • Lowering your stress response with GABA and hierarchical exposure therapy • How energy metabolism and psychological trauma symptoms are related (32:08) Recovering from Veganism & Oxalate Overload • Can you do veganism well? • Addressing the impact of plant toxins and oxalates • The link between chronic pain and oxalate overload • How to reverse the effects of oxalates • The use of biotin to clear oxalates and dosing suggestions • Read: Toxic Superfoods by Sally Norton  • Oxalate dumping symptoms explained  • Advice for recovering vegans • Read: Le Chatelier's principle • Viome: (01:04:09) Methylene Blue: Potential Dangers & Dosage Recommendations • The dangers of combining methylene blue with ayahuasca and psychedelics • Research conclusions on methylene blue dosing • How methylene blue can impact people with Alzheimer’s • Side effects of combining methylene blue with SSRIs • Using methylene blue to help allergy sufferers • ED as a side effect of methylene blue Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Website: Facebook: X: Rumble: YouTube: Gab: Telegram: GETTR: Podcast: Everything You Need To Know About Saturated Fat & Cholesterol with Chris Masterjohn #16 Podcast: Nicotine, the Perfect Psychotropic? Dr. Paul Newhouse # 494 The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 18m
Sep 21
Game-Changing Focus: Play the World’s First FDA-Approved Video Game – Dr. Adam Gazzaley : 1089

If you struggle with retaining sharp focus or have been diagnosed with ADHD or other conditions that impede your brain from functioning at its optimal level, this is the podcast episode for you. We learn about a (literally) out-of-the-box solution to attention training—video games. Yes, you read that right. Our guest today, Dr. Adam Gazzaley, holds an M.D. and Ph.D. in Neuroscience from Mount Sinai School of Medicine and completed Neurology residency at the University of Pennsylvania, followed by postdoctoral training in cognitive neuroscience at UC Berkeley. He's currently the David Dolby Distinguished Professor at UC San Francisco and the Founder/Executive Director of Neuroscape, a center focusing on technology-driven scientific research. So it’s safe to say that Adam is not your prototypical basement gamer. As someone who struggled with focus and attention due to Asperger’s syndrome and brain fog due to the effects of toxic mold exposure, figuring out how to retrain my brain to be able to retain more information and focus longer was one of the first areas of biohacking I ever explored. This is why I’m so excited to be talking all about Endeavor Rx today, the world's first FDA-authorized prescription video game treatment for pediatric ADHD—and Endeavor OTC, for adults who struggle with ADHD, focus, attention, and distraction. We explore how we can measure attention and improvement in focus, the biological systems that control what we focus on consciously and subconsciously, the role of nutrition in our ability to focus, the underlying technology of Endeavor, measuring its effectiveness, and Adam’s vision for how we can use biosensing technology—now and in the future—to optimize awareness, focus, mood, and more.  (03:07) Addressing Modern Attention Challenges • Defining our attention systems and how to measure them • How I learned how to pay attention, even with ADHD • Read: The Distracted Mind by Adam Gazzaley and Larry D. Rosen • Tools we have for addressing attention challenges • What I use now for brain function and focus • The role nutrition plays in being able to focus • What typical of video games can aid in training attention  • The potential negative effects of shooter games  (20:37) Understanding Endeavor: How to Train Attention Using a Video Game • Top down vs. bottom up thinking • Endeavor: the video game that trains your attention$3p=a_google_adwords&$always_deeplink=false&$fallback_url= • The journey of getting Endeavor approved by the FDA • The effectiveness of Endeavor for adults • What to expect from playing Endeavor • How you can utilize multimodal biosensing for quantifying physiology • Hugs from Dr. Love with Paul Zak – #334 • Exploring what technology is used in a sensory immersion lab, including AI (49:21) Exploring Potential Costs & Opportunities of Biosensing Technology • Understanding the potential adverse effects or downsides of this technology • Join the Live Audience: • The exhaustion factor in playing Endeavor • What video games would be likely to reduce cognitive function • Using Lion’s Mane for increasing brain function • What this system could look like in 10 years  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Endeavor OTC: Instagram: Website: Instagram: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 13m
Sep 19
Biohacking Benefits of OMNi-BiOTiC: Supporting Brain Function, Insulin Sensitivity & Detoxification - Hannah Kleinfeld : 1088

I am a sucker for supplements with extensive and impressive research to prove their biohacking benefits, and OMNi-BiOTiC is one of them. Research studies by OMNi-BiOTiC show a 50% or 70% improvement in things like brain function, insulin sensitivity, and detoxification which is really compelling—and exactly why we have Hannah Kleinfield on the show today. Hannah Kleinfeld is the Chief Operating Officer of Allergosan USA, the U.S. joint-venture partner of Institut Allergosan, a global leader in microbiome science and gut health products. She is dedicated to educating about the importance of gut health as a foundation for wellbeing and passionate about helping others experience healthy and vibrant lives.  That passion is clear in today’s episode where she shares the research and broad-ranging benefits of the OMNi-BiOTiC line of probiotic supplements. We talk about why it’s so important to have a thriving gut, the important link between gut health and brain function, what is most likely to harm our guts, especially in the US, and how to find which probiotic is right for you.  If you're into biohacking, whether you're already doing really well and you're looking for what's next, or you've still got that extra 20 pounds that won't budge but you can see you're moving in the right direction, this might be a really big step to help move you toward your goals. If you’d like to try these products for yourself, go to and use code DAVE20 to get 20% off. (02:24) Revitalizing Gut Health with New Technology • Repairing her gut after Lyme disease • The difference between European and US-based supplement brands • Shop OMNi-BiOTiC (use code DAVE20 to get 20% off) • Where to start with probiotics • What is most harmful to the gut (19:25) Probiotic Power: Detoxing, Brain Boosting & Insulin Resistance • How to address a bad bacteria—Clostridium difficile • How a probiotic can change your brain activity • Delivery method of OMNi-BiOTiC • Exploring the benefits of OMNi-BiOTiC Hetox for liver support and insulin resistance • Recommended tests for monitoring what’s going on in your body (34:41) All You Need to Know About Probiotics  • Why OMNi-BiOTiC doesn’t use spores • Pairing OMNi-BiOTiC with other probiotics • What people should know about probiotics • Tips for clearing SIBO • When to take probiotics after being on antibiotics  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Website: (use code DAVE20 to get 20% off) Instagram: @omnibioticlife The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Sep 14
The Science of Sex: Longevity, Pleasure & Performance - Susan Bratton : 1087

Today's episode is with my friend Susan Bratton, who is an intimacy expert with 20 years of experience. She runs a publishing company called Better Lover, and has a supplement company called The 20. Her expertise is in ageless sexuality, sexual biohacking, libido supplementation, and sexual regenerative therapies that roll back the clock on aging. Whether you're a man or a woman, you’ll learn the specific things you can do to change the performance, the shape, the sensitivity, and the longevity of this amazing part of your body.  All life on earth—human and otherwise—runs through the same set of automated decision making that happens before your brain even gets engaged, one of which is what we’ll be talking about today, which keeps the species alive forever. Let’s call it fertility. It is actually a source of nourishment for us. So when you're of the appropriate age, this is as important as eating, breathing and drinking water. Yet, we pay more attention to our food than we do to our reproductive and recreational sides of staying connected to our humanness. That's why Susan's on the show today.  She shares the science behind the link between intimacy and longevity, explains how to prevent atrophy in these important areas of our bodies, dispels myths about self-pleasure, gives a tutorial on all kinds of toys that can increase function and pleasure for all genders, and lists tips for creating more connection and communication in the bedroom. If you want to check out any of the toys or guides mentioned in this episode, go to  (03:14) How to Live Longer by Engaging in More Intimacy • Honoring sexual expression outside of the gender binary • The Human Awareness Institute: • How to regenerate and enhance your sex life • Interesting insight on semen retention • The correlation between regular intimacy and lifespan  • Categories of pleasure toys for men and women  • The benefits of vacuum erection devices and how to use them  • Sexual enhancement products and guides: (26:12) Orgasmic Cross Training: Toys & Supplements to Expand Pleasure Potential • Natural nitric oxide supplements that help reverse atrophy • How Nitric Oxide Controls Oxygen & Nutrient Delivery, Aging & Quality of Life - Nathan Bryan, Ph.D. / Pneuma Nitric Oxide #1041 • Regenerative stack for male and female enhancement • How to fix atrophy and focus on engorgement in female reproductive parts • Orgasmic cross training: 8 different toys for females • How often a man or woman should self-pleasure in order to maintain their potency • The different types of vibrators and their uses (42:02) The Power of Safe & Proper Touch for Female Pleasure  • Orgasmic cross training: 4 different toys for males • Understanding the vulval activation and sensory pleasure women need prior to penetration • Why yoni massages can be so powerful • The effects of shame and lack of proper touch in receiving pleasure for women • The bullseye touch technique: • Sex Life Bucket List: Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  More Dave: Website: Instagram: @susanbratton Facebook: Susan Bratton X: @susanbratton Linkedin: Susan Bratton Blog: Sex Life Bucket List: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 3m
Sep 12
Illuminating Hope: Solutions for Chronic Stress, Pain & Neurological Damage - Dr. Brandon Crawford : 1086

So much of your reality is determined by your brain, and if you have dealt with chronic disease or mental health struggles like me, it can feel like there’s something wrong with you. But, it’s probably not you. It’s probably a brain problem.  Today’s guest, Dr. Brandon Crawford, is here to provide some hope and some answers.  Dr. Brandon Crawford is a board-certified Developmental Functional Neurologist, driven by training from esteemed minds in chiropractic, functional neurology, and functional endocrinology. Renowned as a laser expert, Dr. Crawford shares groundbreaking laser and light therapy protocols in lectures around the world, revolutionizing treatments for various conditions through photobiomodulation.  He has achieved absolutely incredible results helping people rewire their brains and heal chronic conditions at the NeuroSolution Center of Austin. In this conversation, we dive into the really cool technology and research he uses to do it – and share things you can do at home to improve your own brain health. You’ll learn how to hack your brain with light, get an intro to light hygiene, and be educated on the ways we derive energy from light.  We also cover indications of a healthy brain and how to continuously promote brain health, why talk therapy may not be the best way to heal trauma, immediate solutions for when you’re feeling activated by fear, and share advice for parents with kids struggling neurologically after the pandemic mask mandates. (02:36) Optimizing Your Brain With the Right Light • Blue light’s impact on brain tissue • How to combat light toxicity with red light exposure • TrueLight Luminaire: • How OCD can be a superpower • Why lasers are used in the NeuroSolution ESM methodology • Read: The Fourth Phase of Water by Gerald Pollack • A discussion on how we derive energy from light • Practices for getting more sunlight without causing skin harm • How you can hack your brain with light • TrueDark glasses: • 40 years of Zen: (27:50) Tools to Measure Neurological Health & Heal the Vagus Nerve • Leveraging beam physics to heal chronic health conditions combining light and frequency • What to expect from a consultation at NeuroSolution Austin: • How balance indicates neurological health • Is coffee good or bad for the brain? • Danger Coffee: • Why cognitive behavioral therapy may not be as useful as laser therapy • The science behind healing trauma through vagus nerve stimulation • The Birth of LSD with Dr. Stanislav Grof, Father of Transpersonal Psychology #428 (44:21) How to Manage Triggers & Support Kids’ Neurological Development  • How to stop a panic attack or fear paralysis state using breathwork  • How we’ve reinforced ancient practices through science • Vagal nerve hacks for frustration and anger • What stimulating the cymba concha can do for your vagus nerve • How masks have inhibited childrens’ abilities for facial recognition and social engagement • How to restore neurological damage in kids that have occurred over the last 3 years • Things parents can do at home to help kids affected by mask mandates Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  NeuroSolution Austin: Website: Instagram: @neuro_solutions Truedark: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 9m
Sep 07
Reclaim Your Health Freedom: Understanding the Systems Keeping Us Sick - Ivor Cummins : 1085

If you're frustrated with a system prioritizing profit over societal well-being, this episode is pivotal. Today, we dive deep with Ivor Cummins, a Dublin-based biochemical engineer with a knack for simplifying complex topics.  Based on his personal history of insulin resistance and health struggles, he was able to self-heal through nutrition and a low carb diet. In this conversation, we examine the nexus of insulin resistance, heart health, and the current medical system’s failure to diagnose and treat metabolic diseases. Our discussion sheds light on the origins of our current societal framework and its influence on our health and choices. Ivor's unique perspective, combining the understanding of intricate systems in both power and biology, illustrates a clear parallel: We’ve been given systems that aren’t working for the greater good.  In many cases, our health is in our own hands. Mine and Ivor’s stories of weight loss are two of millions examples of that. However, recognizing these facts offers hope, because when you’re informed and aware, you have the freedom to choose what’s right for you, and the confidence to stand up for it.  With that goal in mind, we examine the impact of influential figures like the Rockefellers and J.P. Morgan, discuss what’s going on at the WHO in response to the recent COVID pandemic, and explain the need for distributed versus central governing systems, among many other blockades to true freedom we’re currently facing. Expanding our collective awareness through these conversations is the key to reclaiming control over our lives.  Lastly, I can’t emphasize enough the power of consumer choice. Institutions can't dictate our spending without offering value. There's a peaceful, two-fold solution to our current dilemma— leveraging technology and altering our behaviors. But most importantly, dispelling the pervasive myths that have clouded our understanding and judgment for decades.  (03:22) Ivor’s Journey: Healing Insulin Resistance with a Low Carb Diet • The metaphor behind The Fat Emperor • Test results and research that encouraged Ivor to change his eating habits • What Ivor experienced through trying a low carb diet • How to get your appetite and cravings under control with proper nutrition • The science behind insulin vs. cholesterol • What’s missing in medical training to properly diagnose and heal metabolic syndrome? (24:27) America’s Monopolist Legacy: Shaping Health & Political Systems • Addressing the implications of the new WHO treaty’s verbiage and requirements • Explaining the Pandemic Business Model • The history of the Rockefeller Foundation & United Nations trilateral commission • Dr. Jakob Nordingaard's Interview • J.P. Morgan’s influence on society • The cultural impacts of monopolists’ agendas and propaganda (37:44) The CBDC Threat, Power Dynamics & Achieving Cognitive Freedom • Hidden dangers of the Central Bank Digital Currency • The importance of having a distributed power model vs. central model • What we can do to create positive change in a corrupt system • How to achieve cognitive freedom Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Fat Emperor Podcast: Website: YouTube: @IvorCumminsScience X: @FatEmperor The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Sep 05
Biohacking for Pets: How to Supercharge Your Pet's Health & Longevity - Dr. Gary Richter : 1084

You've heard lots on this show about biohacking, longevity, and how to help your brain and body perform better. But what if you could do the same things for your pet? I've spent most of my life with pets and/or farm animals so I’m thrilled to have my longtime friend, Dr. Gary Richter, America's favorite veterinarian, here to tell you all you need to know about biohacking for your pets. Dr. Gary Richter, DVM, is a distinguished veterinarian, international bestselling author of The Ultimate Pet Health Guide, and founder of Ultimate Pet Nutrition. He’s also the author of two new books, Longevity for Dogs and Longevity for Cats. Dr. Richter is certified in veterinary acupuncture, as well as veterinary chiropractic, understanding the benefits of both conventional and holistic treatment methods. He also places great emphasis on the well-being of the pet owner, knowing that a sick pet can cause great strain on a person's life. Today, we talk about what supplements your pet should be consuming, how you can regenerate their health, genetic testing for pets, what's coming in the future, the things a lot of people believe about pet diets that are absolutely not true, and a bunch of other stuff from a top expert in the field.  All the studies show that having a pet raises your oxytocin. It makes you live longer. It increases heart rate variability. It makes your kids have healthier gut biomes, on and on. Tune in to start learning how to support your pets as well as they support you. 00:03:00 — How Long Can Our Pets Really Live? • The truth about vegan cat food  • How long cats and dogs can live • Why biohacking pets may be easier than for humans • Why dogs like cat poop • The oldest animals he’s worked with  • Physiological differences between dogs and humans  • How much it costs to invest in your pet’s longevity • Pillars of aging for pets  • The root of genomic instability and suggested solutions  00:16:22 — Nutritional Support & Preventative Care for Pets • What to feed your pets for optimal health • Easy and readily available supplements for your pets • Upgrade Labs: • Dave’s experience with electroacupuncture for his dachshund • Documentary: • Testing you can do for your pet to find out predispositions • How much Vitamin D you need in your pet food 00:39:41 — Top Supplements to Support Your Pet’s Optimal Health • Can you and your pet take the same supplements? • What a whole food diet looks like for pets • Benefits of MCT oil for dogs and cats • Read: The Ultimate Pet Health Guide by Dr. Gary Richter • Recommendations for how many supplements your pet needs • Racehorse biohacking • Dr. Richter's supplement list for dog/cat longevity • Read: Longevity for Dogs by Dr. Gary Richter • Read: Longevity for Cats by Dr. Gary Richter • Integrative Veterinary Medicine: • (Use promo code ULTIMATEHEALTH40 for 40% off) Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: Ultimate Pet Nutrition: (Use promo code ULTIMATEHEALTH40 for 40% off) Free Resource: Dr. Richter's supplement list for dog/cat longevity Read: The Ultimate Pet Health Guide by Dr. Gary Richter Read: Longevity for Dogs & Longevity for Cats by Dr. Gary Richter Read: The Ultimate Pet Health Guide by Dr. Gary Richter Integrative Veterinary Medicine: Website: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 3m
Aug 31
Enhance Your Sleep Performance with the Organic, Athlete-Approved Essentia Mattress - Jack Dell'Accio : 1083

Our guest is Jack Dell’Accio, the CEO of Essentia. Essentia has been working on non toxic, organic mattresses for 20 years. Of most importance to Jack is the impact of restorative sleep in terms of recovery from disease, prevention of disease, longevity, and performance.  He's funded a bunch of research on sleep quality and has worked directly with health gurus including myself, professional athletes, various teams in the NBA, NFL, MLS, and over 25% of active NHL players on creating healthy sleep performance. Essentia’s organic mattress has been recognized by several internationally renowned organizations including the Mayo Clinic’s Well Living Lab, and has been named the #1 foam mattress by Consumer Reports for seven consecutive years.  If you're a long time listener or you've read some of my books, you understand how getting a lot of sleep is probably not good for you. If it's more than eight hours, your chances of dying are higher than people who get seven hours a night. The reason I wanted to have Jack on the show today is to go over the latest data on how sleeping on an organic Essentia mattress can improve REM and deep sleep by between 20 and 60 percent.  Remember—it's not the volume, it's the quality of sleep that matters.  Jack provides actionable data on how to improve the quality of your sleep through ensuring your mattress is supporting you from a biological standpoint, so you can make every minute count. We explore what the organic Essentia mattress is made of and the technology that sets it apart from others on the market. We also share our tips for getting the best quality sleep you can get, and how getting regular deep sleep impacts all other areas of your life. 00:02:35 — How Non-Toxic Essentia Mattresses Support Sleep on a Chemical Level • Why athletes aren’t able to sleep well • The number 1 thing impacting your sleep quality  • Environmental toxins’ impact on brain metabolism • Why comfort might not be the most important factor in your mattress • Shop: • How Essentia prevents mold in mattresses • Why putting quartz in mattresses is beneficial for blood cell performance • Exploring the science behind quantum effects 00:26:34 — Unraveling Sleep Secrets: Longevity, Light & Legislation • Measuring heart rate variability to determine quality of sleep • How long the people who live the longest sleep  • True Dark: • The implications of the government’s ban on all incandescent light bulbs • Why there’s legislation around what mattresses are made of • The resistance Jack received from chemists in removing chemicals from mattresses • How a decrease in sleep quality can accelerate the rate of aging  • The Bulletproof Diet: 00:44:40 — Biohacking Rule #1: Prioritize Quality Sleep • The importance of rest for recovery and performance • Sleep: • Mattresses for women versus men • Sleep hacks for temperature management • The specs, content and density of the Essentia Mattress • Upgrade Labs: • Biohacking Conference: • How to determine if a company’s marketing claims are real or fake • Exposing marketing over substance in the mattress industry • Mold Documentary: • What Jack is developing to improve people’s wellness through sleep RESOURCES: UPGRADE YOUR SLEEP TODAY! TAKE ADVANTAGE OF ESSENTIA’S LABOR DAY SALE PLUS USE PROMO CODE DAVE TO GET AN ADDITIONAL $100 OFF YOUR MATTRESS! VISIT MYESSENTIA.COM/DAVEASPREY TO LEARN MORE. Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Instagram: @essentiaorganicmattress YouTube: Essentia Organic Mattress TikTok: @essentiaorganicmattress Jack Dell’Accio: @jackdellaccio The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 10m
Aug 29
Your Home Is Making You Sick: Biohack Your Living Space with Toxin Testing - Ryan Blaser : 1082

The environment you live in has the most profound impact on your health and wellbeing, but are you aware of the toxins and pollutants we’re surrounded by on a daily basis?  That is why today’s episode is so important. We talk about toxins that are overlooked in your house and what you can do about them. Our guest is Ryan Blaser, the founder and CEO of Test My Home, an environmental company dedicated to improving your health by changing the environment around you.  As a functional medicine doctor for your home, Ryan uses his expertise in building biology and healthy home consulting to identify and address toxic sources that could be impacting your health. After a unique personal wellness journey, Ryan founded Test My Home to help others achieve optimal health. He personally experienced the detrimental effects of mold exposure and lead inhalation, which caused unusual and serious health symptoms like fatigue, weight loss, and brain fog. After unsuccessful attempts with conventional doctors, Ryan took the initiative to investigate his home environment and found the source of his health issues.  He cured himself and is now sharing his knowledge and experience with the world. The definition of biohacking is to change the environment around you, and inside of you, so you have full control of your own biology. This is a part of core biohacking, and it's one I think a lot of us just don't think about. We take our supplements, we do our cold plunges, we do all the different biohacks, but just cleaning up the environment around you could make a really big difference. So, in this episode you’ll learn about the most common pollutants and toxins in your home, how to identify them, and ways you can mitigate or eliminate their effects. WE APPRECIATE OUR PARTNERS, CHECK THEM OUT AND GET YOUR DISCOUNT! 5 part healthy home mini course: Test My Home: If booking through the website with TMH's sales team, mention DAVE ASPREY FOR A DISCOUNT! Instagram account for lots of free content: 00:00:17 — The Top 5 Pollutants Indoors & What To Do About Them Ryan’s personal experience getting sick from environmental toxins Moldy Movie: The myth behind green buildings Solutions for toxic mold exposure in residential buildings How to identify mold in the home What you should do if you have a smelly home instead of air fresheners How important is a gas stove vs. an electric range? How lighting affects us and types of lights to use in your home 00:21:30 — Understanding the Dangers of Fragrances, Mold & VOCs The surprising ingredients in candles and air fresheners Homebiotic spray: What to do when you live in humid environments to prevent mold Meridian Upgrade Labs: Tips for dealing with moisture in your home Recommendations to mitigate carbon monoxide dangers Explaining VOCs and how you can absorb or filter them out  The extreme toxicity and effects of formaldehyde  00:42:11 — Sneaky Pollutants: Protecting Your Home from Gas & Noise Symptoms of a leaky sewer gas Ozone pollution versus ozone therapy Sneaky places you can find surface radiation from nuclear plants Protecting yourself from small particles  Reducing noise stressors in the home Learning to listen to your body and intuition to identify toxins or stressors Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Moldy Movie: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 14m
Aug 24
Biohacking in Space: Prioritizing Prevention to Live Forever - Alan Graves : 1081

Alan Graves is the CEO of Do Not Age, a UK-based longevity company, and he’s been fully immersed in the biohacking space since 2019. In that short time, he’s become a leader in supplementation and expanded his curiosities—even as far as outer space. We talk about his preparation for an upcoming Virgin Atlantic flight to the stars, and how he plans to protect his human form in such an environment. We also touch on our dieting journeys—from veganism to all-meat and everything in between, ride the pharmaceutical industry for its ongoing role in promoting sickness in many forms, and sing the praises of Do Not Age’s innovative line of products. From deep space to raspberries, detailed biochemistry to FDA politicization, this episode has it all—as Alan wields an informed and inquisitive perspective on all things biohacking, past, present, and future.  00:01:52 — Going to Space: Preparation, Inspiration & Motivation  • Alan’s preparation to go to space with Virgin Atlantic  • Looking ahead to a total perspective change  • Dave’s family background in aerotech  • Sending a coffee bean to the moon (maybe) • Exclusive: Interview with Ketone Expert Dr. Richard Veech #299 00:08:14 — Avoiding & Counteracting Antinutrients   • Remembering their vegan experiences • Dave’s current diet and how he got there • The Bulletproof Diet by Dave Asprey • Liam Hemsworth and oxalic acid • Why you shouldn't eat raspberries  • Beef vs. chicken vs. fish  00:14:55 — Becoming a Biohacker: How, When & Why? • Realizing longevity can be extended  • Translating scientific papers for the layman • Who paid for the paper? • We Can Slow Down Aging Right Now – David Sinclair, Ph.D. #626 • Investing with integrity  00:22:49 — Do Not Age (DNA) Products & Innovation • Long term view on research at Do Not Age • Taking the hacker approach to business challenges  • Update on NMN’s status in the US • Importance of guaranteed purity  • Breaking down Do Not Age’s resveratrol offering • The role of sirtuins in our body • Resveratrol vs. pterostilbene • Singing the praises of Calcium AKG • Prevention is easier than treatment  00:42:33 — What’s Next? Looking Ahead at Longevity • How long do you think you’ll live? • Artificial intelligence is based on the past, not the future • The rise of collagen peptides • Low cost + high efficacy + data proven • Dosing daily collagen tips  • Dave takes a visit to Walmart headquarters  • Testing for false product claims on Amazon  • How and why to buy the good stuff  Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Do Not Age: Instagram: @do.not.age Facebook: X: @Do_Not_Age The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Aug 22
Super Detergent, Nanobubbles & Living Water: A Whole New World of Wellness - Saba Yussouf : 1080

Dialing in from Dubai, today, we hear from global inventor and investor, Saba Yussouf, about how to position STEM technologies – science, technology, engineering, and math – to prevent infection, treat water, and even fight 100-year problems like climate change. Half business leader and half scientist, herself, she is a futurist, versed in the fine-tuned details of STEM, and putting it all to work through her disruptive investment record around the world. We learn about nanobubbles and their benefit to the brain, unpack the power of intuition and where it comes from, meet the monstrous homunculus, and so much more. We also highlight Saba’s most recent projects, Invisi Smart and Ficks Labs, tip our caps to groundbreaking research of the past, and look to a brighter (and smarter) future in this forward-thinking conversation. If you need to feel good about where the world is headed, and who might lead us there, this is the episode for you. 00:02:06 — Biohacking the Brain: What are Nanobubbles?  • TrueDark anti jet lag glasses • Learning about nanobubbles • Efficient oxygen delivery to the bloodstream • This is your brain on oxygen  • Research: Healthy fats and exclusion-zone size • What else can be delivered through nanobubbles? 00:09:52 — Letting Intuition Be Your Guide   • The marketing vs. engineering innovation death loop  • How did Saba Yussouf learn intuition? (Hint: She didn’t) • Why women tend to know the truth • How do you avoid overthinking your intuition? • Galvanic skin response and muscle testing • The brain cells in our stomach  • Meeting the homunculus • Science is in your heart, not your brain • What it means to be a scientist  00:24:05 — Realizing the Consciousness of Water  • The groundbreaking work of Dr. Masaru Emoto • Why Saba doesn't drink water when processing negative thoughts  • Speaking, or singing, positive affirmations to your water • How ice crystals have been shown to react to music 00:29:09 — Understanding the Innovation Behind Invisi Smart • An update on titania disinfectant technology  • All natural and mineral-based formula  • When the world says “no thanks” to disruptor tech • Invisi Smart and pivoting to cleaning up greenhouse gasses • Saving the world one stinky armpit at a time • What is Ficks Labs? • Disruptive deep science meets affordable luxury • The disinformation in modern advertising Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Invisi Smart: Instagram: @sabayussouf The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Aug 17
Top Tips from the Trainer of Superheroes! – Magnus Lygdbäck

IN THIS EPISODE OF THE HUMAN UPGRADE™, we revisit a conversation Dave had with Magnus Lygdbäck in Spring of 2022. You’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance. Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy. For more than 20 years, he’s trained some of the world’s most recognizable actors, musicians, athletes, artists, and high-performance business entrepreneurs. Musicians like pop stars Katy Perry, Dua Lipa, Harry Styles and Britney Spears. Actors like Gal Gadot for ; Alicia Vikander, for ; Ben Affleck, for and many more. He designed Alexander Skarsgård’s incredible transformation for the lead role as a Viking Berserker in the brand new movie, Even with his “celebrity trainer” title (which he doesn’t love), Magnus is quick to say, “It's not  you train, it's you train.” His MAGNUS METHOD training philosophy embraces the “ethos of an athlete.” This all-inclusive approach to performance includes an athlete’s intensity and structure, while also maintaining balance and energy. Time-zone travel, long days of filming, rehearsals, and the constant demands on a celebrity performer’s time means examining all aspects of fueling, rest and recovery. The same applies to the everyday lives of mere mortals. He encourages being open to learning new things and seeking out discomfort so you can grow. “Look at three things,” Magnus recommends. “One, what do I like to do? No. 2, what does my body need? No. 3, what do I want to master or get better at? That should create your weekly programming.” You already know, and Magnus will remind you, that there are absolutely no life shortcuts to being the superhero of your own life. In this conversation, you’ll find out how much time to spend on your workouts (not as much as you think). “What doesn’t happen in the first hour will not happen in the second,” he says frequently. Even for superheroes. __ __ See Privacy Policy at and California Privacy Notice at

Aug 15
Raise Resilient Minds: How to Help Your Kids Self Regulate & Form Better Habits - Dr. Caroline Leaf : 1078

Today, we’re joined by second-time guest, Dr. Caroline Leaf, to talk about helping kids clean up their mental mess and be more resilient—all based on research from her latest book, How to Help Your Child Clean Up Their Mental Mess. In this episode, Dr. Caroline Leaf shares the best ways for parents to help their kids understand their emotions and build better habits. Dr. Leaf conducts ongoing research and clinical trials in the field of psychoneurobiology in order to improve mental health interventions, many of which she summarizes in this far reaching, informative conversation.  We explore the impact of social media on kids’ anxiety, what parents can do to minimize the mental mess social media can make, and even how to rewire neural patterns it forms. We also dive into the myths of habit formation and how we can break down old habits to form better, new ones.  Dr. Leaf’s expertise doesn't stop there. She also gives a comprehensive explanation of the five steps of the Neurocycle, a tool set for self-regulation and changing your internal programming. 00:01:32 — The Dangers of Social Media & Minimizing Mental Messes • Giving coffee to kids • Danger Coffee: • The mental health crisis kids are facing today • Social media’s role in anxiety in kids • What is a mental mess? • Read: Cleaning Up Your Mental Mess • Avoiding a mental mess while using social media • Read: How to Help Your Child Clean Up Their Mental Mess • How to teach kids to go deep on topics they’re interested in • The science behind how long it takes to build or change a habit 00:27:31 — Habit Hacking 101 • The 5 Steps Neurocycle to rebuild neural networks • The myth of building habits in 21 days • Identifying patterns in habit formation for transforming and healing the brain • How the history of habit formation and brain neuroplasticity has evolved over time • The new standard of care and giving hopeful diagnoses • Empowering ourselves to be the driver of our own health 00:54:37 — Helping Kids Build Resilience • Curiosity as a tool for building resilience in kids • The importance of learning how to self-regulate • How modeling the Neurocycle can help parents and children manage emotions • Why you should double down on what makes you weird • Teaching kids to question everything to filter out what’s real • Removing bias by connecting with others who aren't your age • Helping kids get good sleep Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Read: How to Help Your Child Clean Up Their Mental Mess Read: Cleaning Up Your Mental Mess Website: Facebook: Dr. Caroline Leaf Instagram: @drcarolineleaf YouTube: Dr. Caroline Leaf Podcast: CLEANING UP YOUR MENTAL MESS 5 Steps of Neurocycle Can Clean Up Your Mental Mess – Dr. Caroline Leaf with Dave Asprey – #799 The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 27m
Aug 10
How to Drop Happily Ever After and Do Relationships Better! – John Kim, LMFT : 1077

IN THIS EPISODE OF THE HUMAN UPGRADE you’ll learn how to recognize your own sh*t and be a better partner in relationships.  Want a sustainable partnership? Communicate and apologize; fight without fighting; identify codependent behavior (your own); and manage jealousy (also your own).  This conversation gets into how you can let go of unrealistic ideals of how you think love and relationships should be and live fully in the present. You’ll also get tips on how to be emotionally responsible to people you love every day. Guest John Kim, a licensed marriage and family therapist, as well as a life coach, cracks his life into two big pieces… split on either side of what he calls “the great divide” of his own divorce several years ago. He did the whole “get a tattoo and a Harley” thing to find his way. He also combined what he learned in therapy school with life coaching and technology to be mobile and create online communities. He became known as an unconventional therapist, seeing clients at coffee shops, on hikes, or in a CrossFit box. He’s built a devoted following of fans who love the frank and authentic insights that he—as “The Angry Therapist”—freely shares on social media. TikTok’s his jam, with over 450K people tuning in for his “shot glass” bits of life wisdom. In his book, written with his romantic partner and fellow therapist Vanessa Bennett,  John takes a different (honest, humorous, raw) approach by dissecting his own relationship dynamic to bring clarity to yours. Each part of “IT’S NOT ME, IT’S YOU: Break the Blame Cycle, Relationship Better” gives you questions to ask yourself and practices to do. It’s a book that pushes you into doing and putting your newfound knowledge to IRL use.  Here’s a sneak peek at a few of the LOVE LESSONS (IN A SHOT GLASS) you’ll find in “It’s Not Me, It’s You” __ __ See Privacy Policy at and California Privacy Notice at

Aug 08
Upgrade Spotlight: Next Generation of Nitric Oxide Support with Dr. Myles Spar : 1076

Today's episode is an Upgrade Spotlight edition, where we bring someone on the show who has created something interesting. Our guest today is Dr. Myles Spar, a leading authority in personalized performance medicine as an author, teacher, researcher, TEDx talk speaker, advisor to NBA players, and an Ironman athlete.  In today’s episode, Dr. Spar shares the vast range of benefits of Calroy Health Sciences products, many of which I use in my morning routine, including Arterosil and Vascanox. We talk about the science behind these formulations, and how they help support athletic performance, recovery, cardiovascular health, and even sexual function. If you’re interested in trying these products yourself, you can get 20% off a three-month supply of Arterosil and Vascanox at 00:03:40 — Improve Cardiovascular Health with Vasconox • The correlation between nitric oxide and endurance athletics • Calroy Health Sciences: • Vascanox: • How nitric oxide supports vascular health • How to collaborate with your doctor 00:13:02 — Spotlight on Nitric Oxide & Hydrogen Sulfide • Nitric oxide and aging • Three kinds of nitric oxide in the body • How nitric oxide helps sexual function • An explanation of hydrogen sulfide’s impact on the body 00:20:46 — Why Investing in Quality Supplements is Worthwhile • Arterosil: • Why I invest in 84+ supplements for my morning regimen • The science behind Calroy products • The importance of recovery and optimizing the speed of recovery • Read: Smarter Not Harder • My supplement fix for POTS, Postural Orthostatic Hypotension Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Get 20% off a three-month supply of Arterosil and Vascanox at Website: Facebook: Myles Spar, MD Instagram: @drspar Linkedin: @drspar YouTube: @mdspar The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Aug 04
Upgrade Intervention: Combat Cravings & Candida, Remove Toxins & Feel Your Best - Nadya Green : 1075

Today's episode is a special intervention episode where I work with a member of the Upgrade Collective, my mentorship and membership group, to help them get closer to achieving their health goals. This conversation is all about investigating member Nadya Green’s struggle to lose weight despite following a low carb diet and cycle syncing her eating habits.  Nadya, originally from Russia, has spent her life pursuing an international career in the energy sector. She has worked as an engineer around the globe, including the UK, US, Australia, Egypt, Russia and now Sweden. Becoming a mom at 35 years old has made it ever so critical to be fit and to be able enjoy activities with her family, which is why biohacking and weight loss has become a centerpiece in her life.  We talk about her lab results that point to potential gut issues, estrogen dominance, and mineral deficiencies leading to her cravings, and why her carbophobia may actually be working against her goals. I share with Nadya tools and tips to illustrate all the different pathways that you can use to get the results you want. So, if you're looking at what could be holding you back in your weight loss journey, tune in to hear the advice I gave Nadya about where she could be going wrong, and what to do to help her feel her best. Join the Upgrade Collective to get access to be in the live audience for all of my podcasts, with calls where we all get together and help each other biohack whatever needs biohacking, at  00:01:35 — Why A Low Carb Diet Might Not Help Your Weight Loss Goals • Nadya’s history with extreme fatigue, Hashimoto’s and carbophobia • The impact of the keto diet long-term on metabolism • Toxins related to PCOS and endometriosis • Read: Smarter Not Harder • Environmental & emotional causes of sugar cravings • Symptoms of having active yeast in your gut 00:16:44— Combating Candida: Supplements, Medications & Lifestyle Solutions • Exploring the different ways to combat Candida • My hot take on pharmaceuticals • How to support your detox pathways while on pharmaceuticals • How Candida is related to a sensitivity to cow’s milk • Limiting sugar without eliminating it • Eating what you like in moderation and not being in a perfectionist trap • Cycle syncing your cravings and carbs 00:32:05 — Eat to Feel Amazing: Spotlight On Protein & Minerals • Protein types and amount recommendations • The Bulletproof Diet: • Why new mothers need to pay more attention to their mineral levels • Tps for getting enough electrolytes and offsetting mineral deficiency • Why I recommend eliminating dairy to combat fatigue or brain fog • Helpful supplements for estrogen dominance Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Biohacking Conference: Join the Upgrade Collective: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Aug 03
Finding Radical Wholeness With a Modern-Day Master - Ken Wilber : 1074

Our guest today is a legendary thinker, author, and philosopher. Ken Wilber has spent decades understanding how humans are all interconnected with each other, decoding through dozens of beautifully written books, how we fit into the greater, massive, picture that is the expanding universe. He's an absolute pioneer, a visionary, and that barely scratches the surface of his work. He joins Dave to outline his newest book—Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights—and offers up a supporting stream of consciousness which rivals any that you’d find, on any podcast, in depth of insight and emotional impact. His words resonate with a truth and wonder which will leave you inspired from beginning to end, and well beyond. 00:00:38 — Finding Radical Wholeness with Ken Wilber  • Ken Wilber’s Amazon Author Page • Different ways to explain the general ideas of the world • Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights • Achieving wholeness in our day-to-day • Ken’s first experience of wholeness with the universe • Does a dog have Buddha-nature? • Studying the work of D.T. Suzuki as a young boy • Read: Essays in Zen Buddhism by D.T. Suzuki • Oneness experiences as the core of spirituality • Considering satori as the most precious gift that humankind has 00:18:09 — The Roles Biohacking & Brain Stimulation Play in Unity Experiences  • Electromagnetic brain stimulation for ultimate reality experiences • How brain-mind machines work • Tap Into Your Brain’s Full Potential - Patrick Porter, Ph.D. #869 • How Dave wrote The Bulletproof Diet in gamma state  • What the mind does vs. what the heart does • Ken’s favorite advancements in technology  • Questions remain with regard to quantum unity • Explaining the theta formless state • The Science of Changing Your Mind - Dr. Joe Dispenza #980 00:38:10 — States of Emptiness & How To Get There  • Teachings of Nagarjuna,the%20Madhyamaka%20philosophy%20of%20emptiness. • Formulating the quantum principles • Why all forms of thinking are incomplete  • The four-quadrant pronouns that make it all make sense • Basic tenets of integral theory • Shared objective views, social organism or a collective group • Going deep with Ken Wilber • Are we living in a simulation? • Fourth and fifth states of consciousness 01:08:55 — This is Ken Wilber on Drugs & Nonduality • Psychedelic experiences vs. mystical oneness experiences  • Drugs as a shortcut to masterful meditation • Ken’s bad trip • Stan Grof’s early LSD work  • The Birth of LSD with Dr. Stanislav Grof, Father of Transpersonal Psychology - #428 • Failures of the psychedelic revolution  • Dave’s hand in the ayahuasca boom • Ken Wilber’s awe-inspiring perspective on nonduality  • Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights • Outline of Ken’s latest book  • Stages of operational thinking • Introduction to systems theory  • Appreciating the psychosomatic analysis of Fritz Perls Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now:  Read: Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights Read: Amazon Author Page YouTube: Integral Life The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 47m
Aug 01
Relieve Your Back Pain in 4 Steps! - Dr. Marcella Madera : 1073

IN THIS EPISODE OF THE HUMAN UPGRADE you’ll meet a holistic neurosurgeon who’s evolving spine care  from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means  better healing for you. Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new information about this effective form of regenerative medicine and find out if this treatment may be right for you. “It's a very nuanced discussion,” says Dr. Madera. “It's very patient specific. It's very injury specific.” “The term Aqua really gives a description of what we're trying to create in the body and that is more fluidity,” she explains. “And also, water, aqua, is pure. It’s intense at times, depending on the form. And it is soothing at times, depending on the form. And that is how our treatment goes.” Dr. Madera’s four-part system includes: Reveal, Restore, Revitalize, Revel. You could benefit whether you have an old or new injury, or chronic pain. During this episode, she explains how each part is interconnected and helps you heal your spine, or even knee, problems. The Aqua Method’s three-day immersive experience includes a full team of experts focused on your biology, your energy and your state of mind. Dr. Madera, a board-certified neurosurgeon, trained extensively in conventional medicine. Her expertise in spine care includes surgical treatments, approaches, and techniques for degenerative spine disease, spine tumors, and degenerative deformity.  She started a private practice in in Austin, Texas where she combines her technical spine care with stem cell treatments and holistic modalities like herbs, energy modalities, Chinese healing practices, autogenic training and diet modification. MORE ABOUT DR. MARCELLA MADERA: She’s experienced in open surgery, minimally invasive surgery, endoscopic spine surgery, and regenerative/stem cell procedures. She’s been an assistant professor of Surgery at the University of Texas at Austin Dell Medical School. She also travelled throughout Europe and the U.S. to learn progressive endoscopic techniques and regenerative medicine practices. She completed a Spine Fellowship and faculty instructorship at Johns Hopkins School of Medicine. See Privacy Policy at and California Privacy Notice at

1h 5m
Jul 27
How to Control, Reframe and Change the Chatter in Your Head! – Ethan Kross, Ph.D. : 1072

IN THIS EPISODE OF THE HUMAN UPGRADE you’ll find out how to harness the power of your inner voice to ease anxiety, improve physical and mental health, and deepen your relationship with others.  “The mind is flexible, if we know how to bend it,” says psychologist and award-winning professor Ethan Kross, Ph.D., founder of the Emotion & Self Control Laboratory at the University of Michigan. He’s one of the world’s leading experts in controlling the conscious mind. He studies the ways in which your inner voice impacts your health, performance, decisions and relationships. He explores how people manage their emotions in order to better understand self-control. In particular, the conversations you have with yourself directly impact every part of your health and life. He explain that your inner voice functions to do things like this: __ __ That inner voice can be a powerful tool, giving you creativity, connection and definition. However, when the voice turns to negative and disorienting self-talk (chatter), it can create chaos and overwhelm by zooming into our problems, making you lose perspective. Ethan’s pioneering research mixes behavioral and brain research to get at the “why” behind human nature. He uses insights from his research to give people science-based tools they can use to change their behavior, be used in relationships, support a career move, improve physical performance, decrease stress, increase productivity and be used to reach life goals. You’ll use new tools like mental time travel, tough love and introspection. In this conversation about his book, “CHATTER: The Voice in Our Head, Why It Matters, and How to Harness It,” you’ll learn:  __ __ With Ethan’s experience studying the conscious mind for 20 years, you can learn how to turn negativity into an awesome tool that helps you master your own self-talk. See Privacy Policy at and California Privacy Notice at

1h 10m
Jul 25
Particle Size Matters: Masterclass in Using Silver for Biohacking - Steve Revelli : 1071

Today, on The Human Upgrade, we talk to Steve Revelli about the long history and bright future of using silver nanoparticles as a biohacking silver bullet. Steve's background is in science and education, now serving as the QA Manager at American Biotech Labs, LLC, the brand which produces Silver Biotics—a long-time resident of my own medicine cabinet.  The conversation covers the difference between pathogenic bacteria and probiotics, how silver under a concentration of 40 parts per million can target harmful bacteria while leaving healthy probiotics intact, the importance of nanoparticle size, antibiotic resistance, animal and agricultural applications, and so much more.  You will learn how they use silver in the world of medicine (because they actually do and have for more than a hundred years) and how/when to use it yourself, whether topically, supplementally, or otherwise. This, my free-thinking friends, is a masterclass in using silver for biohacking. 00:03:06 — Retelling the Long Story of Silver • Historical meaning of “born with a silver spoon” • Microbial elements of AG404–why it works • Chemistry deep dive, searching for missing electrons • Why doesn’t silver attack healthy cells? • Differences between prokaryotic cells • More is not always better 00:11:22 — Delivery Systems to Improve Your Health • Importance of nanoparticle sizes in effective use • One warning: avoiding high salt • Using AG404 in nasal spray during air travel • Other off-label uses for Silver Biotics  • Silver particles for immune support  • Topical use for fighting infection  • 70-year medical history of using silver for burns  • Using a vertical sprayer for delivery • Code: DAVE for 30% off at 00:27:09 — Cosmetic Benefits & Antibiotic Resistance • New formulations from Silver Biotics • Wrinkles, acne, cuts, scrapes, etc. • Facial serum vs. skin cream • Fighting antibiotic resistant bacteria  • Pet care and successful applications in agriculture  • Safety an ingestion cycles  • Turning blue from silver toxicity  • Relieving bacterial burden from your sinuses  • Code: DAVE for 30% off at Resources • Shop: Use code DAVE for 30% off at • Instagram: @silverbiotics The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Jul 20
Let Them Eat Dirt: Biohacking Family Nutrition - Andrea Bemis : 1070

Today, we're delving deep into the importance of dirt, not just as soil beneath our feet, but as a key factor in regenerative agriculture and biohacking. Our guest, Andrea Bemis, is an expert in sustainable organic farming and a passionate advocate for nurturing healthy babies and children. Together, we explore the power of the family dinner and the significance of avoiding harmful chemicals and additives in the food we provide for our kids. Andrea Bemis, the brilliant mind behind the farm-to-table blog "Let Them Eat Dirt," joins us as our special guest. She has authored remarkable books, "Dishing Up the Dirt" and "Local Dirt," which provide invaluable insights into creating a healthy and nourishing food environment for children. Through our shared belief in empowering kids to make healthier choices, we aim to guide parents away from the junk and chemicals that can harm their children's well-being and towards more sustainable, locally sourced and economical options. Join us as we share our tips and tales from our own dinner tables, and our top strategies for nourishing your children with whole foods that taste good, too. Welcome, Andrea, to The Human Upgrade.  00:02:07 — Avoiding Processed Foods: Dangers of Heavy Metals & Artificial Sweeteners • How processed foods can change brain chemistry • The mistake parents of young children make when it comes to food • Tips for getting kids to eat diverse foods and flavors • Logistics of living on a farm • Benefits of buying from a CSA • The Baby Food Facts Report findings on sweeteners in baby food • Heavy metals in baby food 00:21:01 — Healthy, Fast & Economical Recipes for Kids • Most economical ways to make healthier baby food at home  • Recommended cooking oils for kids and why • Being mindful of how much kids are snacking • Not forcing your kid to eat when they’re not hungry • Andrea’s fast recipe ideas • How salt impacts babies’ digestive system • Read: Nourishing Traditions by Sally Fallon 00:43:45 — Andrea’s Favorite Sweetener & Farm Life Insights • Andrea’s favorite sweetener for kids • Pros and cons of kale • Finding quality bacon  • The most difficult crops to grow • Teaching your kids where food really comes from • Why small farms are so incredibly important & economical Resources • Website: • Instagram: @andreabemis • CSA: • Read: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Jul 18
1069. What Happens in the Gut, Starts in the Mouth – Naveen Jain : 1069

Today, a dear friend of the show and someone who's disrupted a huge part of the healthcare industry joins us for an informative chat on the critically important oral microbiome—and from a wider perspective—how and why the human body gets sick.  Naveen Jain, founder of Viome—a data company that’s changing the world of health and wellness—goes deep on the latest in anti-aging, what's going on in your mouth and how that affects everything else in your body, the perils of mouthwash, the future of AI-powered analytics, business building with the right priorities in mind, and a whole lot more. And it all comes right back to the base definition, the core understanding, of what biohacking is—using the information and technology around us to live a longer and healthier life. Naveen’s company, Viome, is doing just that. You won’t want to miss this exclusive look into the future—for your own long-term health, or for that of society as a whole. 00:01:44 — What Is It About the Human Body That Causes Us To Be Sick? • Fundamentally changing the way we look at the body  • Dave’s homemade mouthwash and why he stopped using it  • Power of individuality when it comes to health and longevity  • Different impacts of foods on identical twins (Research,to%20weight%20gain%20and%20diabetes.) • What happens in the gut, starts in the mouth  • The signals chewing your food sends to your body • Why a healthy oral microbiome means healthy sex  00:09:33 — Viome: Supercharging Human Data Analytics  • Reading out the transcript from your body • Determining a diet-based source of bad breath  • Viome’s biomarkers and aging score • Looking at RNA va. DNA • Shop and use code DAVE10 to save 10% • Pooling the data from 550,000 samples analyzed • Custom-made diet recommendations for your genetics • Affordability of Viome testing kits  • Predicting mouth and throat cancer at a 95% rate  • Personalized oral microbiome toothpaste gel  00:24:13 — Longevity & Lifespan: Our Health Is Our Wealth • Increasing our healthspan—adding truly viable years • Dave calls out the lifespan cowards • Choosing how and when we die: the ultimate goal for society  • Naveen shares 5 ways to live a long and healthy life  • Nutrition, getting the right fuel for the car • Stress management, escaping fight-or-flight mode • 40 Years of Zen neurofeedback therapy • Why you should quit your shitty stressful job • Smarter Not Harder by Dave Asprey • Prioritizing exercise, 30 minutes a day  • Getting proper sleep, quality vs. quantity  • Sleep with Dave: 14-day sleep challenge 00:37:35 — A Message for the World’s Wantrepreneurs • Find a purpose and live 10 to 15 years longer • Focus on helping people live better—not making more money • Parasitic nature of modern commerce • Amazon’s quality spiral and the race to the bottom  • Impacting the world in your uniquely powerful way • Our success will never be defined by how much money we made Resources Instagram: @viome Instagram: @naveenjainceo Viome: (Code DAVE10 to save 10%) Website: The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

Jul 13
You Control Your Own Karma! – Sadhguru : 1068

IN THIS EPISODE OF THE HUMAN UPGRADE™️...   Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma.  His most recent book, “Karma: A Yogi’s Guide to Crafting Your Destiny,” breaks down the ways in which karma frames our lives. “It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.” See Privacy Policy at and California Privacy Notice at

Jul 11
Happiness Starts with Your Brain Type! – Dr. Daniel Amen : 1067

IN THIS EPISODE OF THE HUMAN UPGRADE™... “Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that.  He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness. “I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.” What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals. Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem. You may be one or a combination of these five primary brain types: (take this brain assessment to find out yours BALANCED: you have a very healthy brain SPONTANEOUS: you have low dopamine PERSISTENT: you’re often worried, rigid, and inflexible SENSITIVE: you need other people and isolation is hard CAUTIOUS: your GABA levels are low Learn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, "You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type” “Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.”   See Privacy Policy at and California Privacy Notice at

1h 21m
Jul 06
You’re Not Crazy, Toxic Mold Exposure Is Poisoning Your Brain - Brian Karr : 1066

If you have all sorts of unexplained health problems in your home, where you work, or where you go to school, symptoms can be very different. One person's gaining fat, another person's always tired, other people have dark circles, emotional irregularity, sudden weight gain, onset of allergies that no one can explain, on and on. In the episode today, you learn the smarter, not harder, ways to deal with toxic mold exposure in your environment from one of the world’s leading experts on the matter.  Our guest is Brian Karr. He's a second-generation indoor environmental consultant and he works with hypersensitive individuals with complex medical conditions. He's the co-founder of We Inspect, an environmental testing company which works to help people understand mold, mycotoxins, and even bacterial toxins that exist in your homes. He takes time to explain what's (usually) there, why it’s important—even down to the genetic level—and what it's doing to you. Go back to the definition of biohacking… The art and science of changing the environment around you and inside of you so that you have full control of your own biology. If your environment is moldy and has biotoxins, maybe you don't have control of your biology—the mold does. Brian's become a go-to guy for medical doctors across the country, helping more than 5,000 people as sensitive as I used to be to create healthier living environments. You're going to learn a lot in this episode, even if you're saying… Well, I don't have a mold problem. You'd be very surprised. 00:17:00 — Meeting the Mold (and Brian) Head On • Dave’s younger years battling his own health  • The xenoestrogen that took over his life • Brian Karr’s background and introduction • We Inspect environmental testing company  • Moldy Movie: • How Brian married into the business and fell in love  • Building an infrastructure to serve the country • Betsy Maldonado’s story  00:15:02 — We Inspect: Spotlighting Innovation & Access  • We Inspect’s process—what’s unique and special? • Most mold is hidden out of plain sight  • Perils of dry mold: more mobile than wet, living mold • The importance of knowing what to look for • Prioritizing innovation and accessibility  • Training program: Mold Finders Method  • Mobile app: We Inspect Together • Pitfalls of other, commercially driven services  00:29:18 — Dealing With Mold in Our Day to Day Lives • Brian’s game plan for getting out of a moldy lease  • Does spraying bleach work? • Why Dave avoids AirBnbs • Homebiotic: • Balancing removal options  • Three easy steps to take in your home • Understanding the Human Cloud Effect  • Gaps in capability of air testing  • Effectiveness of dust sampling  • Find Out If Your Home Is Making You Sick • 100M structures in the US have meaningful mold problems 00:50:04 — Looking Ahead At Life With Less Mold • 90% of structures are exposed to toxic mold • Danger Coffee: • What is truly pure? • Balance of bacteria vs. mold in caves  • Added susceptibility of women and children • 40% of population impacted by mold exposure  • Story time: Dave’s mold-triggered PANDAS WE LOVE OUR SPONSORS! CHECK THEM OUT: • We Inspect environmental testing company  • The Dust Test: • • Moldfinders on Instagram • Brian Karr on LinkedIn • Moldfinders on Facebook • Moldy Movie The Human Upgrade is produced by Crate Media See Privacy Policy at and California Privacy Notice at

1h 9m
Jun 29
Live From The 9th Annual Biohacking Conference: Biohacking the Red Planet with Vera Mulyani : 1065

In this special episode of The Human Upgrade LIVE from the 9th annual Biohacking Conference in Orlando Florida, Dave speaks Vera Mulyani, co-founder of Astrobiome and Mars City Design. Vera discusses the connection between biohacking and living on Mars and emphasizes the importance of designing the Martian environment to control human biology, taking into account mental health and architectural expertise. They also highlight challenges like toxic chemicals in spacecrafts and the need to biohack humans for space. Vera introduces Astrobiome, a microbiome product made from fermented bacteria, designed to optimize gut health in extreme conditions. Success stories demonstrate its effectiveness in improving health and performance. The podcast explores the intersection of biohacking, space exploration, and the significance of microbiome health in Mars-like environments. See Privacy Policy at and California Privacy Notice at

Jun 27
Live From The 9th Annual Biohacking Conference: Protein Panel with Max Lugavere & Dr. Amy Shah : 1064

In this special episode recorded live from the 9th Annual Biohacking conference in Orlando, Dave dives into the vegan vs. animal protein debate with Max Lugavere and Dr. Amy Shah. They explore the reasons behind choosing a vegan lifestyle, including health, reducing animal suffering, and environmental concerns. Max defends animal protein, highlighting its efficiency and amino acid bioavailability, while Dr. Amy advocates for a balance between plant and animal protein, emphasizing the importance of plant fiber for gut health. They discuss studies linking meat consumption to cardiovascular disease and share their personal experiences, ultimately encouraging listeners to find their own balanced approach to protein. They also delve into topics such as protein intake, muscle building, longevity, fasting, circadian-style eating, and the impact of carbohydrates on the body. 9TH ANNUAL BIOHACKING CONFERENCE: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. See Privacy Policy at and California Privacy Notice at

Jun 22
"Unleash Your Sexual Potential: Date Nights, Fantasies, and Healing in 'Smart Sex' with Emily Morse!" : 1063

In this episode, Dave Asprey interviews sex expert Emily Morse about her book "Smart Sex: How to Boost Your Sex IQ and Own Your Pleasure." They discuss the importance of regular date nights for couples and overcoming shame to talk about sexual fantasies. Emily suggests using the "yes/no/maybe" list as a fun way for partners to explore their desires. Real-life examples show how couples transformed their sex lives by addressing physical and emotional challenges. They also touch on therapeutic approaches and the impact of diet on sexual health. Overall, "Smart Sex" offers practical advice for enhancing relationships and enjoying fulfilling sex lives. Watch this episode on YouTube Find all the links and resources in the show notes Check Out Emily's new book "Smart Sex" See Privacy Policy at and California Privacy Notice at

1h 13m
Jun 20
9BC Mini Episode: The Age Reversal Blueprint - Unlocking the Secrets of Functional Genomics for a Youthful, Vibrant Life! : 1062

In this episode of "The Human Upgrade with Dave Asprey," Dave welcomes Kashif Khan from the DNA Company. Kashif shares his journey in functional genomics and how he unintentionally reversed his biological age by 10 years. They discuss the importance of understanding your genome and its impact on aging. Kashif highlights the DNA Company's approach to genetics, focusing on identifying biological functions and finding personalized solutions. They explore the connection between genetics, habits, and aging, emphasizing the need for context-based choices. Kashif also reveals how his genetic profile influenced his gut health and neurochemical balance. Finally, they touch on the role of upbringing and lifestyle in overall health. Don't miss this insightful conversation on unlocking the secrets of functional genomics for a healthier, rejuvenated life. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!  THE DNA COMPANY: 9TH ANNUAL BIOHACKING CONFERENCE: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. IF YOU’RE COMING TO THE CONFERENCE, AFTER KASHIF’S SESSION HE WILL BE SIGNING COPIES OF HIS NEW BOOK,  See Privacy Policy at and California Privacy Notice at

Jun 15
9BC Mini Episode: Unlocking the Secrets of Earthing - The Anti Aging Bed Revolution : 1061

In this episode of "The Human Upgrade with Dave Asprey," Dave discusses the concept of earthing or grounding, a practice he introduced during the early days of the biohacking movement. He explores the benefits of earthing in reducing inflammation and jet lag. Dave introduces Christie Hardison from Anti Aging Bed, who explains their innovative product that combines earthing, photobiomodulation, and antimicrobial silver technology. The bed cover allows users to ground themselves while sleeping, protects against pathogens and EMFs, and uses tourmaline crystals for infrared simulation. Dave and Christie delve into the connection between earthing and other biohacking practices like ozone therapy and the importance of REM sleep. Christie will be speaking about earthing and the Anti Aging Bed at the Biohacking Conference in Orlando. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!  ANTI-AGING BED: 9TH ANNUAL BIOHACKING CONFERENCE: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. See Privacy Policy at and California Privacy Notice at

Jun 14