On today's episode, we chat with Dr. Sheldon Cheskes, principal investigator of the landmark DOSE VF trial. 

In this study, published in the New England Journal of Medicine, Dr. Cheskes and his team wanted to evaluate DSED and VC defibrillation as compared with standard defibrillation in patients who remain in refractory ventricular fibrillation during out-of-hospital cardiac arrest.

In this episode, we walk through the study design, methodology, results, and perhaps most importantly, critically appraise the study to see how it works in the real world!

Timestamps:

02:48: Dr. Cheskes Intro

06:15: Study Intro

16:45: Patients

18:18: Intervention – Vector Change

25:45: Intervention – DSED

37:12: Comparison/Outcome

40:23: Results

54:15: Critical Appraisal