JAMA Author Interviews

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Interviews with leading researchers and thinkers in health care about practice-changing research, innovations, and the most pressing issues facing medicine and health care today from JAMA, the Journal of the American Medical Association.

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798 episodes

Mifepristone–Science, Abortion Care, and Politics

The US Supreme Court will soon decide a case challenging the US Food and Drug Administration’s (FDA’s) approval of mifepristone. Author Holly Fernandez Lynch, JD, MBE, University of Pennsylvania, joins JAMA Executive Editor Gregory Curfman, MD, to discuss the science and politics surrounding this significant case. RELATED CONTENT: __ __

19m
Mar 25
How Do Multimodal Large Language Models Perform on Clinical Vignette Questions?

How did GPT-4 Vision, a model that can work with images and text as input, perform when answering clinical challenge questions from medical journals? Daniel Truhn, MD, MSc, of the University Hospital Aachen in Germany, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss this topic. RELATED CONTENT: __ __

9m
Mar 18
Does Treating Attention-Deficit/Hyperactivity Disorder Reduce Mortality?

An observational study by Lin Li, PhD, and colleagues, published in JAMA, found that pharmacotherapy was associated with reduced mortality in individuals with ADHD. Frances R. Levin, MD, of the Columbia Vagelos College of Physicians and Surgeons, who wrote an accompanying editorial, joins JAMA Associate Editor Donald C. Goff, MD, to discuss the results of this article. RELATED CONTENT: __ __

13m
Mar 12
Delivering Effective Messages in the Patient-Clinician Encounter

Introducing JAMA's new Communicating Medicine series, JAMA Associate Editor Anne Cappola, MD, ScM, discusses strategies for delivering effective messages in the patient encounter with authors Joseph Cappella, PhD, of the University of Pennsylvania, and Richard Street, PhD, of Texas A&M University and Baylor College of Medicine. RELATED CONTENT: __ __

13m
Mar 05
Why Does PrEP Use Lag in Cisgender Women?

How will new study results inform HIV prevention in the US and globally? JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Jeanne Marrazzo, MD, MPH, director of NIAID, discuss these study findings and more. RELATED CONTENT: __ __

11m
Mar 01
Updated Pediatric Sepsis Criteria—Transitioning From SIRS to Phoenix

JAMA Associate Editor Romain Pirracchio, MD, MPH, discusses context and implications of the new pediatric sepsis criteria with authors Hallie Prescott, MD, MSc, of the University of Michigan and Ann Arbor VA Hospital, and Roberto Jabornisky, MD, of Northeastern National Medical School in Argentina. RELATED CONTENT: __ __

14m
Feb 27
Renter Eviction, Excess Mortality, and COVID-19

Renters who received eviction filings experienced excess mortality associated with the COVID-19 pandemic. JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses a recent study that underscores the importance of studying health outcomes among marginalized populations with author Nick Graetz, PhD, from Princeton University. RELATED CONTENT: __ __

12m
Feb 20
Azithromycin to Prevent Childhood Mortality in Sub-Saharan Africa

Childhood death rates remain high in some areas of sub-Saharan Africa, despite global reductions in childhood mortality. JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Thomas Lietman, MD, University of California, San Francisco, discuss twice-yearly azithromycin to reduce childhood mortality. RELATED CONTENT: __ __

10m
Feb 13
Evaluating the Effectiveness of Bivalent COVID-19 Vaccines in Children and Adolescents

Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. RELATED CONTENT: __ __

12m
Feb 06
Anxiety and Depression Symptoms After the Dobbs Abortion Rights Decision

Following the Dobbs decision, females aged 18-45 years living in states with “trigger laws” that restricted access to abortion reported a greater increase in symptoms of anxiety and depression than those in states without trigger laws. JAMA Associate Editor Donald Goff, MD, speaks with editorialist Julia Steinberg, PhD, associate professor at the School of Public Health at the University of Maryland, about this topic. RELATED CONTENT: __ __

14m
Jan 23
Patient-Centered Palliative Care

JAMA Deputy Editor Preeti Malani, MD, MSJ, and author Alexander K. Smith, MD, MS, MPH, University of California, San Francisco, discuss the importance of 2 new palliative care trials that were recently published in JAMA. RELATED CONTENT: __ __

14m
Jan 16
Dialysis Facility Performance and Social Risk in the First Year of the ESRD Treatment Choices Model

Dialysis facilities in the US are financially rewarded for higher rates of home dialysis and kidney transplant, but facilities that serve patients with high social risk might have a harder time meeting these goals. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, speaks with Amal N. Trivedi, MD, MPH, of Brown University, about how this plays out under the ESRD Treatment Choices Model. RELATED CONTENT: __ __

14m
Jan 09
Alpha-Gal Syndrome

Alpha-gal syndrome is a food allergy to red meat products that develops after affected individuals are bitten by a tick. JAMA Deputy Editor Kristin Walter, MD, MS, discusses alpha-gal syndrome with author Mariel R. Benjamin, MD, assistant professor in the Division of Allergy and Clinical Immunology at Michigan Medicine. RELATED CONTENT: __ __

8m
Jan 02
Private Equity Acquisition and Hospital-Acquired Adverse Events in the US

The effects of private equity acquisition of US hospitals on the quality of inpatient care and patient outcomes remain largely unknown. JAMA Associate Editor Karen E. Joynt Maddox, MD, MPH, spoke with author Zirui Song, MD, PHD, of Boston General Hospital, about a recent study showing that private equity acquisition was associated with increased hospital-acquired adverse events. RELATED CONTENT: __ __

13m
Dec 26, 2023
Effect of Dietary Sodium on Blood Pressure

Does reducing dietary sodium benefit patients already taking antihypertensive medication? JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, speaks with author Norrina Allen, PhD, MPH, from Northwestern University, about the effect of dietary sodium on blood pressure. RELATED CONTENT: __ __

14m
Dec 19, 2023
Risks Associated With Cannabis Exposure During Pregnancy

Cannabis use is increasing among reproductive-age individuals. JAMA Deputy Editor Linda Brubaker, MD, MS, discusses the associated risks of cannabis exposure during pregnancy with Torri D. Metz, MD, MS, University of Utah Health. RELATED CONTENT: __ __

10m
Dec 12, 2023
Neonatal Outcomes Following Serial Amnioinfusions for Bilateral Renal Agenesis

Bilateral renal agenesis results in lethal neonatal pulmonary hypoplasia. New evidence from an amnioinfusion trial is available. JAMA Deputy Editor Linda Brubaker, MD, MS, discusses the results from the Renal Anhydramnios Fetal Therapy Trial with Meredith A. Atkinson, MD, MHS, Johns Hopkins University, and Johnathan M. Davis, MD, Tufts University. RELATED CONTENT: __ __

13m
Dec 05, 2023
Increasing Cervical Cancer Screening With Self-Sampling HPV Kits at Home

Cervical cancer screening is effective when done as recommended. JAMA Deputy Editor Linda Brubaker, MD, speaks with Rachel L. Winer, PhD, MPH, of the University of Washington, about a recent trial in JAMA that compared cervical cancer screening strategies, including direct-mail and opt-in approaches for human papillomavirus (HPV) self-sampling. RELATED CONTENT: __ __

10m
Nov 28, 2023
Small-Volume Blood Collection Tubes May Reduce Transfusions in Intensive Care

Small-volume blood collection tubes may decrease red blood cell transfusions in intensive care units without affecting laboratory analysis. JAMA Associate Editor Christopher W. Seymour, MD, MSc, discusses the results and implications of the STRATUS trial with Deborah M. Siegal, MD, MSc, of Ottawa Hospital Research Institute. RELATED CONTENT: __ __

16m
Nov 21, 2023
Fitness Trackers to Guide Advice on Activity Prescription

Fitness trackers are a group of devices including watches, phones, and rings that track physical activity. JAMA Executive Editor Gregory Curfman, MD, speaks with I-Min Lee, MBBS, ScD, professor of medicine at Harvard Medical School and professor of epidemiology at Harvard T.H. Chan School of Public Health, about using fitness trackers to guide advice on activity prescription. RELATED CONTENT: __ __

15m
Nov 14, 2023
Medicare’s Historic Prescription Drug Price Negotiations

JAMA Senior Editor Kristin Walter, MD, MS, and Lawrence O. Gostin, JD, JAMA Legal and Global Health Correspondent and Faculty Director of the O’Neill Institute for National and Global Health Law at Georgetown University, discuss the Inflation Reduction Act, which for the first time allows the Centers for Medicare & Medicaid Services to negotiate prescription drug prices with drug manufacturers. RELATED CONTENT: __ __

15m
Nov 07, 2023
Traditional Chinese Medicine Meets Evidence-Based Medicine in the Acutely Infarcted Heart

JAMA Executive Editor Gregory Curfman, MD, speaks with Richard G. Bach, MD, professor of medicine and medical director of the cardiac intensive care unit at the Washington University School of Medicine in St. Louis, about the use of traditional Chinese medicine to treat patients with acute ST-segment elevation myocardial infarction. RELATED CONTENT: __ __

19m
Oct 24, 2023
Optical Coherence Tomography (OCT): Imaging Modalities in Clinical Practice

Optical coherence tomography (OCT) is a powerful imaging tool used across multiple clinical disciplines. JAMA Executive Editor Gregory Curfman, MD, speaks with 2023 Lasker Award recipient James G. Fujimoto, PhD, professor of electrical engineering at MIT, about his role in developing OCT and OCT’s advancements in clinical practice. RELATED CONTENT: __ __

11m
Oct 17, 2023
Nasal Iodophor vs Nasal Mupirocin With Chlorhexidine Baths to Prevent Infections in Adult ICUs

Nasal mupirocin plus chlorhexidine baths in ICUs prevents methicillin-resistant Staphylococcus aureus (MRSA) infections but raises concern about antibiotic resistance. JAMA Senior Editor Kristin Walter, MD, speaks with Susan Huang, MD, of University of California, Irvine, about a study comparing iodophor vs mupirocin with chlorhexidine bathing for ICU-attributable S aureus clinical cultures. RELATED CONTENT: __ __

13m
Oct 10, 2023
Is Remote Ischemic Conditioning (RIC) an Effective Treatment for Acute Stroke?

It’s been unclear whether remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is an effective treatment for acute stroke. JAMA Deputy Editor Chris Muth, MD, speaks with author Rolf Blauenfeldt, MD, Aarhus University Hospital, Denmark, about the RESIST randomized clinical trial, which looks at the effect of RIC when initiated in the prehospital setting. RELATED CONTENT: __ __

11m
Oct 03, 2023
The Connection Between SARS-CoV-2 and Type 1 Diabetes Risk in Young Children

During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. RELATED CONTENT: __ __

14m
Sep 26, 2023
Two-Year Outcomes After Minimally Invasive Surfactant Therapy

Many premature infants with respiratory distress are now supported with continuous positive airway pressure, or CPAP, rather than intubation and ventilation, and those with CPAP can receive surfactant via a minimally invasive approach. JAMA Associate Editor Tracy Lieu, MD, speaks with author Peter Dargaville, MD, from the Menzies Institute for Medical Research in Tasmania, Australia, about Two-Year Outcomes After Minimally Invasive Surfactant Therapy in Preterm Infants: Follow-Up of the OPTIMIST-A Randomized Clinical Trial. RELATED CONTENT: __ __

15m
Sep 19, 2023
Sedentary Behavior and Dementia

There is an established link between sedentary behavior and cardiovascular disease, but the association between sedentary behavior and dementia is unclear. JAMA Deputy Editor Christopher C. Muth, MD, speaks with David A. Raichlen, PhD, University of Southern California, about a new study that investigates the relationship between sedentary behavior and dementia in older adults. RELATED CONTENT: __ __

10m
Sep 12, 2023
Psilocybin for Major Depressive Disorder

In a new study, psilocybin showed promise as a treatment for major depressive disorder (MDD). JAMA Associate Editor Donald C. Goff, MD, speaks with author Charles L. Raison, MD, from the Usona Institute, about the study, as well as Rachel Yehuda, PhD, Mount Sinai School of Medicine, who wrote an accompanying editorial about the potential benefits of psychedelic therapies. RELATED CONTENT: __ __

28m
Aug 31, 2023
Neurodevelopmental Effects of Antenatal IV Magnesium Sulfate Between 30-34 Weeks' Gestation

Magnesium sulfate is widely recommended for neuroprotection in pregnancies at risk of preterm delivery. However, the optimal gestational age for use is unclear. JAMA Associate Editor Melissa Simon, MD, MPH, and Caroline Crowther, MD, Liggins Institute, University of Auckland, discuss the use of magnesium sulfate at different gestational ages and potential benefit vs harms as reflected in the MAGENTA Trial. RELATED CONTENT: __ __

13m
Aug 15, 2023